CPXCR1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHMP3	CPXCR1	ENSP00000263856	ENSP00000276127	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	CPX chromosome region candidate 1.	0.540
CHMP3	VTA1	ENSP00000263856	ENSP00000356602	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Vacuolar protein sorting-associated protein VTA1 homolog; Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involv [...]	0.957
CPXCR1	CHMP3	ENSP00000276127	ENSP00000263856	CPX chromosome region candidate 1.	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	0.540
CPXCR1	CYLC1	ENSP00000276127	ENSP00000331556	CPX chromosome region candidate 1.	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	0.566
CPXCR1	FAM24A	ENSP00000276127	ENSP00000357889	CPX chromosome region candidate 1.	Protein FAM24A; Family with sequence similarity 24 member A.	0.577
CPXCR1	FAM9A	ENSP00000276127	ENSP00000440163	CPX chromosome region candidate 1.	Protein FAM9A; Family with sequence similarity 9 member A.	0.493
CPXCR1	IQCF6	ENSP00000276127	ENSP00000381760	CPX chromosome region candidate 1.	IQ motif containing F6.	0.476
CPXCR1	KLHL4	ENSP00000276127	ENSP00000362206	CPX chromosome region candidate 1.	Kelch-like protein 4; Kelch like family member 4.	0.632
CPXCR1	MAGEB2	ENSP00000276127	ENSP00000368273	CPX chromosome region candidate 1.	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	0.471
CPXCR1	SATL1	ENSP00000276127	ENSP00000425421	CPX chromosome region candidate 1.	Spermidine/spermine N1-acetyl transferase like 1.	0.492
CPXCR1	TGIF2LX	ENSP00000276127	ENSP00000453704	CPX chromosome region candidate 1.	Homeobox protein TGIF2LX; May have a transcription role in testis.	0.492
CPXCR1	VTA1	ENSP00000276127	ENSP00000356602	CPX chromosome region candidate 1.	Vacuolar protein sorting-associated protein VTA1 homolog; Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involv [...]	0.745
CYLC1	CPXCR1	ENSP00000331556	ENSP00000276127	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	CPX chromosome region candidate 1.	0.566
CYLC1	KLHL4	ENSP00000331556	ENSP00000362206	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	Kelch-like protein 4; Kelch like family member 4.	0.414
CYLC1	SATL1	ENSP00000331556	ENSP00000425421	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	Spermidine/spermine N1-acetyl transferase like 1.	0.544
FAM24A	CPXCR1	ENSP00000357889	ENSP00000276127	Protein FAM24A; Family with sequence similarity 24 member A.	CPX chromosome region candidate 1.	0.577
FAM24A	IQCF6	ENSP00000357889	ENSP00000381760	Protein FAM24A; Family with sequence similarity 24 member A.	IQ motif containing F6.	0.590
FAM9A	CPXCR1	ENSP00000440163	ENSP00000276127	Protein FAM9A; Family with sequence similarity 9 member A.	CPX chromosome region candidate 1.	0.493
IQCF6	CPXCR1	ENSP00000381760	ENSP00000276127	IQ motif containing F6.	CPX chromosome region candidate 1.	0.476
IQCF6	FAM24A	ENSP00000381760	ENSP00000357889	IQ motif containing F6.	Protein FAM24A; Family with sequence similarity 24 member A.	0.590