| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP1M1 | MPZL2 | ENSP00000388996 | ENSP00000278937 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.538 |
| EVA1A | MPZL2 | ENSP00000377490 | ENSP00000278937 | Protein eva-1 homolog A; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.520 |
| MFAP3L | MPZL2 | ENSP00000354583 | ENSP00000278937 | Microfibrillar-associated protein 3-like; May participate in the nuclear signaling of EGFR and MAPK1/ERK2. May a have a role in metastasis. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.440 |
| MPZL2 | AP1M1 | ENSP00000278937 | ENSP00000388996 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | 0.538 |
| MPZL2 | EVA1A | ENSP00000278937 | ENSP00000377490 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Protein eva-1 homolog A; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. | 0.520 |
| MPZL2 | MFAP3L | ENSP00000278937 | ENSP00000354583 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Microfibrillar-associated protein 3-like; May participate in the nuclear signaling of EGFR and MAPK1/ERK2. May a have a role in metastasis. | 0.440 |
| MPZL2 | MPZL3 | ENSP00000278937 | ENSP00000278949 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Myelin protein zero-like protein 3; Mediates homophilic cell-cell adhesion; Belongs to the myelin P0 protein family. | 0.898 |
| MPZL2 | OCLN | ENSP00000278937 | ENSP00000347379 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. | 0.401 |
| MPZL2 | PRRG4 | ENSP00000278937 | ENSP00000257836 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family. | 0.496 |
| MPZL2 | RAG2 | ENSP00000278937 | ENSP00000478672 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] | 0.487 |
| MPZL2 | TMEM26 | ENSP00000278937 | ENSP00000382237 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Transmembrane protein 26. | 0.579 |
| MPZL2 | TSHZ3 | ENSP00000278937 | ENSP00000240587 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Teashirt homolog 3; Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway func [...] | 0.455 |
| MPZL3 | MPZL2 | ENSP00000278949 | ENSP00000278937 | Myelin protein zero-like protein 3; Mediates homophilic cell-cell adhesion; Belongs to the myelin P0 protein family. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.898 |
| OCLN | MPZL2 | ENSP00000347379 | ENSP00000278937 | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.401 |
| PRRG4 | MPZL2 | ENSP00000257836 | ENSP00000278937 | Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.496 |
| RAG2 | MPZL2 | ENSP00000478672 | ENSP00000278937 | V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.487 |
| TMEM26 | MPZL2 | ENSP00000382237 | ENSP00000278937 | Transmembrane protein 26. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.579 |
| TSHZ3 | MPZL2 | ENSP00000240587 | ENSP00000278937 | Teashirt homolog 3; Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway func [...] | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.455 |
