Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EVA1A | MPZL2 | ENSP00000377490 | ENSP00000278937 | Protein eva-1 homolog A; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.610 |
| MPZL2 | EVA1A | ENSP00000278937 | ENSP00000377490 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Protein eva-1 homolog A; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. | 0.610 |
| MPZL2 | MPZL3 | ENSP00000278937 | ENSP00000278949 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Myelin protein zero-like protein 3; Mediates homophilic cell-cell adhesion; Belongs to the myelin P0 protein family. | 0.585 |
| MPZL2 | OCLN | ENSP00000278937 | ENSP00000347379 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. | 0.590 |
| MPZL2 | PRRG4 | ENSP00000278937 | ENSP00000257836 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family. | 0.466 |
| MPZL2 | RAG2 | ENSP00000278937 | ENSP00000478672 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] | 0.489 |
| MPZL2 | ROBO1 | ENSP00000278937 | ENSP00000420321 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Roundabout homolog 1; Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its intera [...] | 0.474 |
| MPZL2 | ROBO2 | ENSP00000278937 | ENSP00000417335 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Roundabout homolog 2; Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development; Belongs to the immunoglobulin superfamily. ROBO family. | 0.475 |
| MPZL2 | TMEM26 | ENSP00000278937 | ENSP00000382237 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Transmembrane protein 26. | 0.505 |
| MPZL2 | TSHZ3 | ENSP00000278937 | ENSP00000240587 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Teashirt homolog 3; Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway func [...] | 0.455 |
| MPZL2 | USE1 | ENSP00000278937 | ENSP00000263897 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER. | 0.633 |
| MPZL3 | MPZL2 | ENSP00000278949 | ENSP00000278937 | Myelin protein zero-like protein 3; Mediates homophilic cell-cell adhesion; Belongs to the myelin P0 protein family. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.585 |
| OCLN | MPZL2 | ENSP00000347379 | ENSP00000278937 | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.590 |
| PRRG4 | MPZL2 | ENSP00000257836 | ENSP00000278937 | Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.466 |
| RAG2 | MPZL2 | ENSP00000478672 | ENSP00000278937 | V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.489 |
| ROBO1 | MPZL2 | ENSP00000420321 | ENSP00000278937 | Roundabout homolog 1; Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its intera [...] | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.474 |
| ROBO1 | ROBO2 | ENSP00000420321 | ENSP00000417335 | Roundabout homolog 1; Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its intera [...] | Roundabout homolog 2; Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development; Belongs to the immunoglobulin superfamily. ROBO family. | 0.666 |
| ROBO1 | USE1 | ENSP00000420321 | ENSP00000263897 | Roundabout homolog 1; Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its intera [...] | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER. | 0.447 |
| ROBO2 | MPZL2 | ENSP00000417335 | ENSP00000278937 | Roundabout homolog 2; Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development; Belongs to the immunoglobulin superfamily. ROBO family. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.475 |
| ROBO2 | ROBO1 | ENSP00000417335 | ENSP00000420321 | Roundabout homolog 2; Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development; Belongs to the immunoglobulin superfamily. ROBO family. | Roundabout homolog 1; Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its intera [...] | 0.666 |
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