STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UHRF1BP1LUHRF1-binding protein 1-like; UHRF1 binding protein 1 like. (1464 aa)    
Predicted Functional Partners:
STX6
Syntaxin-6; Involved in intracellular vesicle trafficking.
   
 
 0.818
GPATCH2L
G patch domain-containing protein 2-like; G-patch domain containing 2 like.
   
  
 0.642
RND2
Rho-related GTP-binding protein RhoN; May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity).
    
  0.555
PRR36
Proline-rich protein 36; Proline rich 36.
      
 0.506
DMXL1
DmX-like protein 1; Dmx like 1.
   
  
 0.497
ZNF407
Zinc finger protein 407; May be involved in transcriptional regulation.
   
  
 0.435
VPS13C
Vacuolar protein sorting-associated protein 13C; Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization.
   
  
 0.434
PTPRH
Receptor-type tyrosine-protein phosphatase H; Protein phosphatase that may contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion-associated substrates and thus negatively regulating integrin- promoted signaling processes. Induces apoptotic cell death by at least two distinct mechanisms: inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. Inhibits the basal activity of LCK and its activation in response to TCR stimulation and TCR-induced activat [...]
      
 0.431
ZNF829
Zinc finger protein 829; May be involved in transcriptional regulation.
      
 0.431
CT55
Cancer/testis antigen 55.
   
   0.429
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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