| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC65 | CCDC83 | ENSP00000312706 | ENSP00000280245 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Coiled-coil domain containing 83. | 0.683 |
| CCDC65 | IQCG | ENSP00000312706 | ENSP00000265239 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Dynein regulatory complex protein 9; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility. | 0.523 |
| CCDC83 | CCDC65 | ENSP00000280245 | ENSP00000312706 | Coiled-coil domain containing 83. | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | 0.683 |
| CCDC83 | CDADC1 | ENSP00000280245 | ENSP00000251108 | Coiled-coil domain containing 83. | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.583 |
| CCDC83 | DMRTC2 | ENSP00000280245 | ENSP00000269945 | Coiled-coil domain containing 83. | Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development. | 0.466 |
| CCDC83 | EIF4ENIF1 | ENSP00000280245 | ENSP00000380659 | Coiled-coil domain containing 83. | Eukaryotic translation initiation factor 4E transporter; Nucleoplasmic shuttling protein, which inhibits translation initiation. Mediates the nuclear import of EIF4E by a piggy-back mechanism. | 0.447 |
| CCDC83 | FMR1NB | ENSP00000280245 | ENSP00000359498 | Coiled-coil domain containing 83. | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. | 0.529 |
| CCDC83 | IQCF1 | ENSP00000280245 | ENSP00000307958 | Coiled-coil domain containing 83. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.628 |
| CCDC83 | IQCG | ENSP00000280245 | ENSP00000265239 | Coiled-coil domain containing 83. | Dynein regulatory complex protein 9; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility. | 0.572 |
| CCDC83 | KLHL10 | ENSP00000280245 | ENSP00000293303 | Coiled-coil domain containing 83. | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | 0.470 |
| CCDC83 | RPH3AL | ENSP00000280245 | ENSP00000328977 | Coiled-coil domain containing 83. | Rab effector Noc2; Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells. | 0.510 |
| CCDC83 | SPAG9 | ENSP00000280245 | ENSP00000262013 | Coiled-coil domain containing 83. | C-Jun-amino-terminal kinase-interacting protein 4; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. | 0.539 |
| CDADC1 | CCDC83 | ENSP00000251108 | ENSP00000280245 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Coiled-coil domain containing 83. | 0.583 |
| CDADC1 | DMRTC2 | ENSP00000251108 | ENSP00000269945 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development. | 0.420 |
| CDADC1 | EIF4ENIF1 | ENSP00000251108 | ENSP00000380659 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Eukaryotic translation initiation factor 4E transporter; Nucleoplasmic shuttling protein, which inhibits translation initiation. Mediates the nuclear import of EIF4E by a piggy-back mechanism. | 0.407 |
| CDADC1 | IQCG | ENSP00000251108 | ENSP00000265239 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Dynein regulatory complex protein 9; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility. | 0.446 |
| DMRTC2 | CCDC83 | ENSP00000269945 | ENSP00000280245 | Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development. | Coiled-coil domain containing 83. | 0.466 |
| DMRTC2 | CDADC1 | ENSP00000269945 | ENSP00000251108 | Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development. | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.420 |
| DMRTC2 | IQCF1 | ENSP00000269945 | ENSP00000307958 | Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.467 |
| EIF4ENIF1 | CCDC83 | ENSP00000380659 | ENSP00000280245 | Eukaryotic translation initiation factor 4E transporter; Nucleoplasmic shuttling protein, which inhibits translation initiation. Mediates the nuclear import of EIF4E by a piggy-back mechanism. | Coiled-coil domain containing 83. | 0.447 |