UBALD1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX19B	NEMP1	ENSP00000455813	ENSP00000300128	ATP-dependent RNA helicase DDX19B; DEAD-box helicase 19B.	Nuclear envelope integral membrane protein 1.	0.522
DDX19B	UBALD1	ENSP00000455813	ENSP00000283474	ATP-dependent RNA helicase DDX19B; DEAD-box helicase 19B.	UBA-like domain-containing protein 1; UBA like domain containing 1.	0.558
MLYCD	UBALD1	ENSP00000262430	ENSP00000283474	Malonyl-CoA decarboxylase, mitochondrial; Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in mus [...]	UBA-like domain-containing protein 1; UBA like domain containing 1.	0.596
NEMP1	DDX19B	ENSP00000300128	ENSP00000455813	Nuclear envelope integral membrane protein 1.	ATP-dependent RNA helicase DDX19B; DEAD-box helicase 19B.	0.522
NEMP1	PANK2	ENSP00000300128	ENSP00000313377	Nuclear envelope integral membrane protein 1.	Pantothenate kinase 2, mitochondrial; May be the master regulator of the CoA biosynthesis. Belongs to the type II pantothenate kinase family.	0.510
NEMP1	UBALD1	ENSP00000300128	ENSP00000283474	Nuclear envelope integral membrane protein 1.	UBA-like domain-containing protein 1; UBA like domain containing 1.	0.652
PANK2	NEMP1	ENSP00000313377	ENSP00000300128	Pantothenate kinase 2, mitochondrial; May be the master regulator of the CoA biosynthesis. Belongs to the type II pantothenate kinase family.	Nuclear envelope integral membrane protein 1.	0.510
PANK2	UBALD1	ENSP00000313377	ENSP00000283474	Pantothenate kinase 2, mitochondrial; May be the master regulator of the CoA biosynthesis. Belongs to the type II pantothenate kinase family.	UBA-like domain-containing protein 1; UBA like domain containing 1.	0.487
TMEM86B	UBALD1	ENSP00000321038	ENSP00000283474	Lysoplasmalogenase; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties; Belongs to the TMEM86 family.	UBA-like domain-containing protein 1; UBA like domain containing 1.	0.426
TMEM86B	ZNF628	ENSP00000321038	ENSP00000469591	Lysoplasmalogenase; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties; Belongs to the TMEM86 family.	Zinc finger protein 628; Transcription activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3' (By similarity).	0.405
UBALD1	DDX19B	ENSP00000283474	ENSP00000455813	UBA-like domain-containing protein 1; UBA like domain containing 1.	ATP-dependent RNA helicase DDX19B; DEAD-box helicase 19B.	0.558
UBALD1	MLYCD	ENSP00000283474	ENSP00000262430	UBA-like domain-containing protein 1; UBA like domain containing 1.	Malonyl-CoA decarboxylase, mitochondrial; Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in mus [...]	0.596
UBALD1	NEMP1	ENSP00000283474	ENSP00000300128	UBA-like domain-containing protein 1; UBA like domain containing 1.	Nuclear envelope integral membrane protein 1.	0.652
UBALD1	PANK2	ENSP00000283474	ENSP00000313377	UBA-like domain-containing protein 1; UBA like domain containing 1.	Pantothenate kinase 2, mitochondrial; May be the master regulator of the CoA biosynthesis. Belongs to the type II pantothenate kinase family.	0.487
UBALD1	TMEM86B	ENSP00000283474	ENSP00000321038	UBA-like domain-containing protein 1; UBA like domain containing 1.	Lysoplasmalogenase; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties; Belongs to the TMEM86 family.	0.426
UBALD1	ZBTB45	ENSP00000283474	ENSP00000346603	UBA-like domain-containing protein 1; UBA like domain containing 1.	Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	0.413
UBALD1	ZNF628	ENSP00000283474	ENSP00000469591	UBA-like domain-containing protein 1; UBA like domain containing 1.	Zinc finger protein 628; Transcription activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3' (By similarity).	0.470
ZBTB45	UBALD1	ENSP00000346603	ENSP00000283474	Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	UBA-like domain-containing protein 1; UBA like domain containing 1.	0.413
ZNF628	TMEM86B	ENSP00000469591	ENSP00000321038	Zinc finger protein 628; Transcription activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3' (By similarity).	Lysoplasmalogenase; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties; Belongs to the TMEM86 family.	0.405
ZNF628	UBALD1	ENSP00000469591	ENSP00000283474	Zinc finger protein 628; Transcription activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3' (By similarity).	UBA-like domain-containing protein 1; UBA like domain containing 1.	0.470