C7orf31 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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co-expression

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gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	C11orf1	ENSP00000410186	ENSP00000260276	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	0.788
AK9	C7orf31	ENSP00000410186	ENSP00000283905	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.833
AK9	EFCAB6	ENSP00000410186	ENSP00000262726	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.706
AK9	ODF3B	ENSP00000410186	ENSP00000382804	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.	Outer dense fiber of sperm tails 3B.	0.408
AK9	TEKT5	ENSP00000410186	ENSP00000283025	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.	Tektin-5; May be a structural component of the sperm flagellum.	0.432
C11orf1	AK9	ENSP00000260276	ENSP00000410186	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.	0.788
C11orf1	C7orf31	ENSP00000260276	ENSP00000283905	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.872
C11orf1	EFCAB6	ENSP00000260276	ENSP00000262726	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.852
C11orf1	EFHC2	ENSP00000260276	ENSP00000404232	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.846
C11orf1	FAM166A	ENSP00000260276	ENSP00000344729	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Protein FAM166A; Family with sequence similarity 166 member A.	0.641
C11orf1	ODF3B	ENSP00000260276	ENSP00000382804	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Outer dense fiber of sperm tails 3B.	0.832
C11orf1	TEKT3	ENSP00000260276	ENSP00000379263	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility.	0.856
C11orf1	TEKT5	ENSP00000260276	ENSP00000283025	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Tektin-5; May be a structural component of the sperm flagellum.	0.663
C7orf31	AK9	ENSP00000283905	ENSP00000410186	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.	0.833
C7orf31	C11orf1	ENSP00000283905	ENSP00000260276	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	0.872
C7orf31	CCIN	ENSP00000283905	ENSP00000334996	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.	0.863
C7orf31	EFCAB6	ENSP00000283905	ENSP00000262726	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.891
C7orf31	EFHC2	ENSP00000283905	ENSP00000404232	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.878
C7orf31	FAM166A	ENSP00000283905	ENSP00000344729	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Protein FAM166A; Family with sequence similarity 166 member A.	0.834
C7orf31	KLHL40	ENSP00000283905	ENSP00000287777	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity).	0.872