STRINGSTRING
TRIM42 protein (human) - STRING interaction network
"TRIM42" - Tripartite motif-containing protein 42 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
TRIM42Tripartite motif-containing protein 42; Protein phosphatase 1 regulatory subunits; Belongs to the TRIM/RBCC family (723 aa)    
Predicted Functional Partners:
SDCBP
Syntenin-1; Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1- mediated SMAD2/3 activation and TGFB1-induced epithelial-to- mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6I [...] (298 aa)
       
 
  0.672
ACTL9
Actin-like protein 9; Actin related proteins (416 aa)
     
      0.646
TRIM77
Tripartite motif containing 77; Belongs to the TRIM/RBCC family (450 aa)
     
   
  0.638
CAPZA3
F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) (299 aa)
     
        0.562
TRIM64
Tripartite motif containing 64; Belongs to the TRIM/RBCC family (449 aa)
           
  0.559
PLCZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is [...] (608 aa)
     
        0.546
TRAT1
T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells (186 aa)
           
  0.538
TRIM59
Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways; Ring finger proteins (403 aa)
           
  0.537
TRIM60
Tripartite motif containing 60; Belongs to the TRIM/RBCC family (471 aa)
           
  0.537
PCDHB9
Protocadherin beta-9; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (797 aa)
       
 
  0.533
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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