node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC1 | ARMC12 | ENSP00000276569 | ENSP00000288065 | Armadillo repeat containing 1. | Armadillo repeat containing 12. | 0.586 |
ARMC12 | ARMC1 | ENSP00000288065 | ENSP00000276569 | Armadillo repeat containing 12. | Armadillo repeat containing 1. | 0.586 |
ARMC12 | C1orf226 | ENSP00000288065 | ENSP00000413150 | Armadillo repeat containing 12. | Uncharacterized protein C1orf226; Chromosome 1 open reading frame 226. | 0.427 |
ARMC12 | CCDC54 | ENSP00000288065 | ENSP00000261058 | Armadillo repeat containing 12. | Coiled-coil domain containing 54. | 0.432 |
ARMC12 | FCRL5 | ENSP00000288065 | ENSP00000354691 | Armadillo repeat containing 12. | Fc receptor-like protein 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. | 0.421 |
ARMC12 | KLHL40 | ENSP00000288065 | ENSP00000287777 | Armadillo repeat containing 12. | Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity). | 0.459 |
ARMC12 | RBBP4 | ENSP00000288065 | ENSP00000362592 | Armadillo repeat containing 12. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.843 |
ARMC12 | TBC1D21 | ENSP00000288065 | ENSP00000300504 | Armadillo repeat containing 12. | TBC1 domain family member 21; May act as a GTPase-activating protein for Rab family protein(s). May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possibly by regulating RAB3A activity. | 0.628 |
ARMC12 | TEX38 | ENSP00000288065 | ENSP00000455854 | Armadillo repeat containing 12. | Testis-expressed protein 38; Testis expressed 38. | 0.423 |
ARMC12 | TRIM7 | ENSP00000288065 | ENSP00000274773 | Armadillo repeat containing 12. | E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation. Belongs to the TRIM/RBCC family. | 0.459 |
ARMC12 | VDAC3 | ENSP00000288065 | ENSP00000428845 | Armadillo repeat containing 12. | Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. | 0.426 |
C1orf226 | ARMC12 | ENSP00000413150 | ENSP00000288065 | Uncharacterized protein C1orf226; Chromosome 1 open reading frame 226. | Armadillo repeat containing 12. | 0.427 |
CCDC54 | ARMC12 | ENSP00000261058 | ENSP00000288065 | Coiled-coil domain containing 54. | Armadillo repeat containing 12. | 0.432 |
FCRL5 | ARMC12 | ENSP00000354691 | ENSP00000288065 | Fc receptor-like protein 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. | Armadillo repeat containing 12. | 0.421 |
KLHL40 | ARMC12 | ENSP00000287777 | ENSP00000288065 | Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity). | Armadillo repeat containing 12. | 0.459 |
KLHL40 | TRIM7 | ENSP00000287777 | ENSP00000274773 | Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity). | E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation. Belongs to the TRIM/RBCC family. | 0.470 |
RBBP4 | ARMC12 | ENSP00000362592 | ENSP00000288065 | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | Armadillo repeat containing 12. | 0.843 |
TBC1D21 | ARMC12 | ENSP00000300504 | ENSP00000288065 | TBC1 domain family member 21; May act as a GTPase-activating protein for Rab family protein(s). May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possibly by regulating RAB3A activity. | Armadillo repeat containing 12. | 0.628 |
TBC1D21 | VDAC3 | ENSP00000300504 | ENSP00000428845 | TBC1 domain family member 21; May act as a GTPase-activating protein for Rab family protein(s). May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possibly by regulating RAB3A activity. | Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. | 0.429 |
TEX38 | ARMC12 | ENSP00000455854 | ENSP00000288065 | Testis-expressed protein 38; Testis expressed 38. | Armadillo repeat containing 12. | 0.423 |