CATIP protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRD9	CATIP	ENSP00000419765	ENSP00000289388	Bromodomain-containing protein 9; Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA- histone contacts within a nucleosome in an ATP-dependent manner.	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	0.799
CATIP	BRD9	ENSP00000289388	ENSP00000419765	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Bromodomain-containing protein 9; Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA- histone contacts within a nucleosome in an ATP-dependent manner.	0.799
CATIP	CFAP299	ENSP00000289388	ENSP00000425786	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	0.646
CATIP	CFAP44	ENSP00000289388	ENSP00000377428	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.703
CATIP	CFAP58	ENSP00000289388	ENSP00000358718	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Cilia and flagella associated protein 58; Belongs to the CFAP58 family.	0.746
CATIP	DNAH1	ENSP00000289388	ENSP00000401514	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family.	0.718
CATIP	FOPNL	ENSP00000289388	ENSP00000461830	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	LisH domain-containing protein FOPNL; Involved in the biogenesis of cilia. Required for the recruitment of PLK1 to centrosomes and S phase progression.	0.636
CATIP	GAS8	ENSP00000289388	ENSP00000268699	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh [...]	0.787
CATIP	ROPN1	ENSP00000289388	ENSP00000184183	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family.	0.662
CATIP	ROPN1B	ENSP00000289388	ENSP00000426271	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family.	0.644
CATIP	ROPN1L	ENSP00000289388	ENSP00000421405	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.	0.796
CFAP299	CATIP	ENSP00000425786	ENSP00000289388	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	0.646
CFAP299	CFAP44	ENSP00000425786	ENSP00000377428	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.636
CFAP299	CFAP58	ENSP00000425786	ENSP00000358718	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	Cilia and flagella associated protein 58; Belongs to the CFAP58 family.	0.676
CFAP299	DNAH1	ENSP00000425786	ENSP00000401514	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family.	0.632
CFAP299	GAS8	ENSP00000425786	ENSP00000268699	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh [...]	0.701
CFAP299	ROPN1L	ENSP00000425786	ENSP00000421405	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.	0.635
CFAP44	CATIP	ENSP00000377428	ENSP00000289388	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	0.703
CFAP44	CFAP299	ENSP00000377428	ENSP00000425786	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.	0.636
CFAP44	CFAP58	ENSP00000377428	ENSP00000358718	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	Cilia and flagella associated protein 58; Belongs to the CFAP58 family.	0.967