| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKRD16 | ANKRD18B | ENSP00000369436 | ENSP00000290943 | Ankyrin repeat domain-containing protein 16; Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. | Ankyrin repeat domain 18B. | 0.424 |
| ANKRD16 | RFXANK | ENSP00000369436 | ENSP00000305071 | Ankyrin repeat domain-containing protein 16; Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | 0.497 |
| ANKRD18B | ANKRD16 | ENSP00000290943 | ENSP00000369436 | Ankyrin repeat domain 18B. | Ankyrin repeat domain-containing protein 16; Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. | 0.424 |
| ANKRD18B | ASB9 | ENSP00000290943 | ENSP00000369855 | Ankyrin repeat domain 18B. | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin- Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Belongs to the ankyrin SOCS box (ASB) family. | 0.430 |
| ANKRD18B | C1orf131 | ENSP00000290943 | ENSP00000355609 | Ankyrin repeat domain 18B. | Uncharacterized protein C1orf131; Chromosome 1 open reading frame 131. | 0.541 |
| ANKRD18B | CCDC198 | ENSP00000290943 | ENSP00000392368 | Ankyrin repeat domain 18B. | Uncharacterized protein CCDC198; Coiled-coil domain containing 198. | 0.478 |
| ANKRD18B | PRSS3 | ENSP00000290943 | ENSP00000354280 | Ankyrin repeat domain 18B. | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | 0.496 |
| ANKRD18B | RFXANK | ENSP00000290943 | ENSP00000305071 | Ankyrin repeat domain 18B. | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | 0.434 |
| ANKRD18B | RLF | ENSP00000290943 | ENSP00000361857 | Ankyrin repeat domain 18B. | Zinc finger protein Rlf; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.473 |
| ANKRD18B | THAP8 | ENSP00000290943 | ENSP00000292894 | Ankyrin repeat domain 18B. | THAP domain containing 8. | 0.570 |
| ASB9 | ANKRD18B | ENSP00000369855 | ENSP00000290943 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin- Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Belongs to the ankyrin SOCS box (ASB) family. | Ankyrin repeat domain 18B. | 0.430 |
| ASB9 | RFXANK | ENSP00000369855 | ENSP00000305071 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin- Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Belongs to the ankyrin SOCS box (ASB) family. | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | 0.525 |
| C1orf131 | ANKRD18B | ENSP00000355609 | ENSP00000290943 | Uncharacterized protein C1orf131; Chromosome 1 open reading frame 131. | Ankyrin repeat domain 18B. | 0.541 |
| CCDC198 | ANKRD18B | ENSP00000392368 | ENSP00000290943 | Uncharacterized protein CCDC198; Coiled-coil domain containing 198. | Ankyrin repeat domain 18B. | 0.478 |
| PRSS3 | ANKRD18B | ENSP00000354280 | ENSP00000290943 | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | Ankyrin repeat domain 18B. | 0.496 |
| RFXANK | ANKRD16 | ENSP00000305071 | ENSP00000369436 | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | Ankyrin repeat domain-containing protein 16; Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. | 0.497 |
| RFXANK | ANKRD18B | ENSP00000305071 | ENSP00000290943 | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | Ankyrin repeat domain 18B. | 0.434 |
| RFXANK | ASB9 | ENSP00000305071 | ENSP00000369855 | DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1 (By similarity). | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin- Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Belongs to the ankyrin SOCS box (ASB) family. | 0.525 |
| RLF | ANKRD18B | ENSP00000361857 | ENSP00000290943 | Zinc finger protein Rlf; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Ankyrin repeat domain 18B. | 0.473 |
| THAP8 | ANKRD18B | ENSP00000292894 | ENSP00000290943 | THAP domain containing 8. | Ankyrin repeat domain 18B. | 0.570 |