MRNIP protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAU	MRNIP	ENSP00000431822	ENSP00000292586	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	0.977
FAU	RPL14	ENSP00000431822	ENSP00000379506	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family.	0.999
FAU	RPL18A	ENSP00000431822	ENSP00000222247	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family.	0.999
FAU	RPL23	ENSP00000431822	ENSP00000420311	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein L23.	0.999
FAU	RPL38	ENSP00000431822	ENSP00000309830	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	0.999
FAU	RPL5	ENSP00000431822	ENSP00000359345	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.999
FAU	RPL6	ENSP00000431822	ENSP00000403172	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family.	0.999
FAU	RPS17	ENSP00000431822	ENSP00000498019	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S17.	0.999
FAU	RPS18	ENSP00000431822	ENSP00000393241	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.	0.999
FAU	RPS26	ENSP00000431822	ENSP00000348849	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.999
MRNIP	FAU	ENSP00000292586	ENSP00000431822	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	0.977
MRNIP	RPL14	ENSP00000292586	ENSP00000379506	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family.	0.959
MRNIP	RPL18A	ENSP00000292586	ENSP00000222247	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	Ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family.	0.958
MRNIP	RPL23	ENSP00000292586	ENSP00000420311	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	Ribosomal protein L23.	0.968
MRNIP	RPL38	ENSP00000292586	ENSP00000309830	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	0.959
MRNIP	RPL5	ENSP00000292586	ENSP00000359345	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.959
MRNIP	RPL6	ENSP00000292586	ENSP00000403172	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	60S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family.	0.961
MRNIP	RPS17	ENSP00000292586	ENSP00000498019	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	Ribosomal protein S17.	0.969
MRNIP	RPS18	ENSP00000292586	ENSP00000393241	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.	0.960
MRNIP	RPS26	ENSP00000292586	ENSP00000348849	MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.	Ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.970