STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC116Coiled-coil domain containing 116. (613 aa)    
Predicted Functional Partners:
PAPSS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Required [...]
    
   0.785
GNL1
Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.
    
   0.785
CCDC96
Coiled-coil domain containing 96.
      
 0.585
C7orf31
Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.
      
 0.583
C4orf47
UPF0602 protein C4orf47; Chromosome 4 open reading frame 47; Belongs to the UPF0602 family.
   
  
 0.580
CCDC38
Coiled-coil domain containing 38.
   
  
 0.562
TEX37
Testis-expressed sequence 37 protein; Testis expressed 37.
   
  
 0.542
EFCAB5
EF-hand calcium-binding domain-containing protein 5; EF-hand calcium binding domain 5.
   
  
 0.511
C5orf52
Uncharacterized protein C5orf52; Chromosome 5 open reading frame 52.
      
 0.506
YDJC
Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family.
   
  
 0.500
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.