C6orf136 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCF1	C6orf136	ENSP00000313603	ENSP00000293604	ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	0.490
ABCF1	GNL1	ENSP00000313603	ENSP00000365806	ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	0.504
ABCF1	TCF19	ENSP00000313603	ENSP00000365433	ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.	Transcription factor 19; Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.	0.510
C12orf56	C6orf136	ENSP00000446101	ENSP00000293604	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	0.439
C6orf136	ABCF1	ENSP00000293604	ENSP00000313603	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.	0.490
C6orf136	C12orf56	ENSP00000293604	ENSP00000446101	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	0.439
C6orf136	GLT8D1	ENSP00000293604	ENSP00000266014	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	Glycosyltransferase 8 domain containing 1; Belongs to the glycosyltransferase 8 family.	0.475
C6orf136	GNL1	ENSP00000293604	ENSP00000365806	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	0.521
C6orf136	GTF2H4	ENSP00000293604	ENSP00000259895	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...]	0.473
C6orf136	NRM	ENSP00000293604	ENSP00000259953	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	Nurim.	0.537
C6orf136	PAFAH1B3	ENSP00000293604	ENSP00000444935	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	Platelet-activating factor acetylhydrolase IB subunit gamma; Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain; Belongs to the 'GDSL' lipolytic enzyme family. Platelet- activating factor acetylhydrolase IB beta/gamma subunits subfamily.	0.511
C6orf136	TCF19	ENSP00000293604	ENSP00000365433	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	Transcription factor 19; Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.	0.469
GLT8D1	C6orf136	ENSP00000266014	ENSP00000293604	Glycosyltransferase 8 domain containing 1; Belongs to the glycosyltransferase 8 family.	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	0.475
GNL1	ABCF1	ENSP00000365806	ENSP00000313603	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.	0.504
GNL1	C6orf136	ENSP00000365806	ENSP00000293604	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	0.521
GNL1	GTF2H4	ENSP00000365806	ENSP00000259895	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...]	0.457
GNL1	NRM	ENSP00000365806	ENSP00000259953	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	Nurim.	0.465
GNL1	TCF19	ENSP00000365806	ENSP00000365433	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	Transcription factor 19; Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.	0.510
GTF2H4	C6orf136	ENSP00000259895	ENSP00000293604	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...]	Uncharacterized protein C6orf136; Chromosome 6 open reading frame 136.	0.473
GTF2H4	GNL1	ENSP00000259895	ENSP00000365806	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...]	Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.	0.457