node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DSG4 | KRT25 | ENSP00000352785 | ENSP00000310573 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | 0.548 |
DSG4 | KRT33B | ENSP00000352785 | ENSP00000251646 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.625 |
DSG4 | KRT38 | ENSP00000352785 | ENSP00000246646 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family. | 0.626 |
DSG4 | KRT71 | ENSP00000352785 | ENSP00000267119 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | 0.571 |
DSG4 | KRT82 | ENSP00000352785 | ENSP00000257974 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cuticular Hb2; Keratin 82; Belongs to the intermediate filament family. | 0.713 |
DSG4 | KRT83 | ENSP00000352785 | ENSP00000293670 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cuticular Hb3; Keratin 83; Belongs to the intermediate filament family. | 0.913 |
DSG4 | KRT86 | ENSP00000352785 | ENSP00000444533 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cuticular Hb6. | 0.885 |
DSG4 | KRTAP3-1 | ENSP00000352785 | ENSP00000375430 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.665 |
KRT25 | DSG4 | ENSP00000310573 | ENSP00000352785 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | 0.548 |
KRT25 | KRT33B | ENSP00000310573 | ENSP00000251646 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.592 |
KRT25 | KRT38 | ENSP00000310573 | ENSP00000246646 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family. | 0.522 |
KRT25 | KRT71 | ENSP00000310573 | ENSP00000267119 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | 0.875 |
KRT25 | KRT82 | ENSP00000310573 | ENSP00000257974 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type II cuticular Hb2; Keratin 82; Belongs to the intermediate filament family. | 0.460 |
KRT25 | KRT83 | ENSP00000310573 | ENSP00000293670 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type II cuticular Hb3; Keratin 83; Belongs to the intermediate filament family. | 0.616 |
KRT25 | KRT86 | ENSP00000310573 | ENSP00000444533 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type II cuticular Hb6. | 0.454 |
KRT25 | KRTAP1-1 | ENSP00000310573 | ENSP00000305975 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin-associated protein 1-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.468 |
KRT25 | KRTAP3-1 | ENSP00000310573 | ENSP00000375430 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.510 |
KRT25 | KRTAP3-3 | ENSP00000310573 | ENSP00000375428 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin-associated protein 3-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 3 family. | 0.402 |
KRT33B | DSG4 | ENSP00000251646 | ENSP00000352785 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | 0.625 |
KRT33B | KRT25 | ENSP00000251646 | ENSP00000310573 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | 0.592 |