STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM71AProtein FAM71A; Family with sequence similarity 71 member A; Belongs to the FAM71 family (594 aa)    
Predicted Functional Partners:
ENSG00000233024
LOC339047 protein; Nuclear pore complex-interacting protein family member A5; Protein LOC101930008
      
 0.681
NPIPA5
Nuclear pore complex interacting protein family member A5
      
 0.681
RAB2B
Ras-related protein Rab-2B; Required for protein transport from the endoplasmic reticulum to the Golgi complex; RAB, member RAS oncogene GTPases
    
 
 0.676
PEBP4
Phosphatidylethanolamine-binding protein 4; Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization; Belongs to the phosphatidylethanolamine-binding protein family
      
 0.622
MORN5
MORN repeat containing 5
      
 0.621
C2orf73
Uncharacterized protein C2orf73; Chromosome 2 open reading frame 73
   
  
 0.527
EFR3A
Protein EFR3 homolog A; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3A probably acts as the membrane-anchoring component. Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect
      
 0.526
CCNYL1
Cyclin-Y-like protein 1; Cyclin Y like 1; Belongs to the cyclin family
   
  
 0.516
KBTBD7
Kelch repeat and BTB domain containing 7
      
 0.456
DDX26B
Integrator complex subunit 6-like; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
      
 0.454
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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