STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1orf115Uncharacterized protein C1orf115; Chromosome 1 open reading frame 115 (142 aa)    
Predicted Functional Partners:
TMEM220
Transmembrane protein 220
      
 0.536
C9orf16
UPF0184 protein C9orf16; Chromosome 9 open reading frame 16
      
 0.535
ZNF177
Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family
      
 0.528
ENSG00000270011
ZNF559-ZNF177 readthrough; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family
      
 0.525
AGAP5
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5; Putative GTPase-activating protein; Ankyrin repeat domain containing
      
 0.512
TMEM71
Transmembrane protein 71; Belongs to the TMEM71 family
      
 0.510
C5orf15
Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15
      
 0.473
VEPH1
Ventricular zone-expressed PH domain-containing protein homolog 1; Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling; Armadillo-like helical domain containing
      
 0.446
PPDPF
Pancreatic progenitor cell differentiation and proliferation factor; Probable regulator of exocrine pancreas development
      
 0.444
CNTD2
Cyclin N-terminal domain containing 2
      
 0.442
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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