node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP9 | DTNA | ENSP00000219919 | ENSP00000470152 | Aquaporin-9; Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | 0.476 |
AQP9 | DTNB | ENSP00000219919 | ENSP00000384084 | Aquaporin-9; Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Dystrobrevin beta. | 0.504 |
AQP9 | PPP1R21 | ENSP00000219919 | ENSP00000294952 | Aquaporin-9; Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.574 |
C12orf4 | CRYZL1 | ENSP00000261250 | ENSP00000370966 | Protein C12orf4; Plays a role in mast cell degranulation. | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.627 |
C12orf4 | GATD1 | ENSP00000261250 | ENSP00000321691 | Protein C12orf4; Plays a role in mast cell degranulation. | Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family. | 0.402 |
C12orf4 | PPP1R21 | ENSP00000261250 | ENSP00000294952 | Protein C12orf4; Plays a role in mast cell degranulation. | Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.818 |
C12orf4 | TBCK | ENSP00000261250 | ENSP00000378198 | Protein C12orf4; Plays a role in mast cell degranulation. | TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization. | 0.892 |
CRYZL1 | C12orf4 | ENSP00000370966 | ENSP00000261250 | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Protein C12orf4; Plays a role in mast cell degranulation. | 0.627 |
CRYZL1 | GATD1 | ENSP00000370966 | ENSP00000321691 | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family. | 0.819 |
CRYZL1 | PPP1R21 | ENSP00000370966 | ENSP00000294952 | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.942 |
DTNA | AQP9 | ENSP00000470152 | ENSP00000219919 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | Aquaporin-9; Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.476 |
DTNA | HMX3 | ENSP00000470152 | ENSP00000350549 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS (By similarity); Belongs to the HMX homeobox family. | 0.580 |
DTNA | PPP1R21 | ENSP00000470152 | ENSP00000294952 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.840 |
DTNA | RSPH3 | ENSP00000470152 | ENSP00000252655 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia. Belongs to the flagellar radial spoke RSP3 family. | 0.840 |
DTNB | AQP9 | ENSP00000384084 | ENSP00000219919 | Dystrobrevin beta. | Aquaporin-9; Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.504 |
DTNB | HMX3 | ENSP00000384084 | ENSP00000350549 | Dystrobrevin beta. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS (By similarity); Belongs to the HMX homeobox family. | 0.580 |
DTNB | PPP1R21 | ENSP00000384084 | ENSP00000294952 | Dystrobrevin beta. | Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.841 |
DTNB | RSPH3 | ENSP00000384084 | ENSP00000252655 | Dystrobrevin beta. | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia. Belongs to the flagellar radial spoke RSP3 family. | 0.840 |
GATD1 | C12orf4 | ENSP00000321691 | ENSP00000261250 | Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family. | Protein C12orf4; Plays a role in mast cell degranulation. | 0.402 |
GATD1 | CRYZL1 | ENSP00000321691 | ENSP00000370966 | Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family. | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.819 |