FAM228A protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP20	CFAP70	ENSP00000262498	ENSP00000310829	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	0.677
CFAP20	DLEC1	ENSP00000262498	ENSP00000308597	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Deleted in lung and esophageal cancer protein 1; May act as a tumor suppressor by inhibiting cell proliferation.	0.642
CFAP20	FAM228A	ENSP00000262498	ENSP00000295150	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Protein FAM228A; Family with sequence similarity 228 member A; Belongs to the FAM228 family.	0.461
CFAP20	GOT1L1	ENSP00000262498	ENSP00000303077	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Putative aspartate aminotransferase, cytoplasmic 2; Glutamic-oxaloacetic transaminase 1 like 1.	0.641
CFAP20	KIF9	ENSP00000262498	ENSP00000333942	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Kinesin-like protein KIF9; Kinesin family member 9.	0.641
CFAP20	LRGUK	ENSP00000262498	ENSP00000285928	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.	0.641
CFAP20	MAP1S	ENSP00000262498	ENSP00000325313	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family.	0.641
CFAP20	SPAG17	ENSP00000262498	ENSP00000337804	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts.	0.641
CFAP20	SPATA17	ENSP00000262498	ENSP00000355900	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Spermatogenesis-associated protein 17; Spermatogenesis associated 17.	0.641
CFAP20	SPATA4	ENSP00000262498	ENSP00000280191	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.	0.641
CFAP70	CFAP20	ENSP00000310829	ENSP00000262498	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	0.677
CFAP70	DLEC1	ENSP00000310829	ENSP00000308597	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Deleted in lung and esophageal cancer protein 1; May act as a tumor suppressor by inhibiting cell proliferation.	0.812
CFAP70	FAM228A	ENSP00000310829	ENSP00000295150	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Protein FAM228A; Family with sequence similarity 228 member A; Belongs to the FAM228 family.	0.465
CFAP70	GOT1L1	ENSP00000310829	ENSP00000303077	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Putative aspartate aminotransferase, cytoplasmic 2; Glutamic-oxaloacetic transaminase 1 like 1.	0.641
CFAP70	KIF9	ENSP00000310829	ENSP00000333942	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Kinesin-like protein KIF9; Kinesin family member 9.	0.699
CFAP70	LRGUK	ENSP00000310829	ENSP00000285928	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.	0.776
CFAP70	MAP1S	ENSP00000310829	ENSP00000325313	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family.	0.641
CFAP70	SPAG17	ENSP00000310829	ENSP00000337804	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts.	0.837
CFAP70	SPATA17	ENSP00000310829	ENSP00000355900	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Spermatogenesis-associated protein 17; Spermatogenesis associated 17.	0.721
CFAP70	SPATA4	ENSP00000310829	ENSP00000280191	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.	0.642