STRINGSTRING
FAM228A protein (human) - STRING interaction network
"FAM228A" - Protein FAM228A in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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Experiments
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[Homology]
Score
FAM228AProtein FAM228A; Family with sequence similarity 228 member A; Belongs to the FAM228 family (206 aa)    
Predicted Functional Partners:
RFX8
DNA-binding protein RFX8; May be a transcription factor; Regulatory factor X family (473 aa)
           
  0.646
TMEM71
Transmembrane protein 71; Belongs to the TMEM71 family (276 aa)
           
  0.645
PFN4
Profilin-4; Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin, contrary to other family members; Belongs to the profilin family (129 aa)
     
   
  0.633
SPATA17
Spermatogenesis-associated protein 17; Spermatogenesis associated 17 (361 aa)
           
  0.585
FAM174B
Membrane protein FAM174B; Family with sequence similarity 174 member B (159 aa)
           
  0.583
GDPD4
Glycerophosphodiester phosphodiesterase domain containing 4; Belongs to the glycerophosphoryl diester phosphodiesterase family (520 aa)
           
  0.557
ITSN2
Intersectin-2; Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes; C2 domain containing (1697 aa)
           
  0.543
DHX35
Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily (703 aa)
           
  0.538
CEP162
Centrosomal protein of 162 kDa; Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules; Belongs to the CEP162 family (1403 aa)
           
  0.533
TPRA1
Transmembrane protein adipocyte associated 1; 7TM orphan receptors (373 aa)
           
  0.529
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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