Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCDC140Coiled-coil domain-containing protein 140; CCDC140 long non-coding RNA. (163 aa)    
Predicted Functional Partners:
RPL3
60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
    
   0.811
RPL26L1
Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family.
    
   0.811
RPL26
60S ribosomal protein L26; Component of the large ribosomal subunit.
    
   0.811
RGS13
Regulator of G-protein signaling 13; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha (By similarity).
   
   0.633
C3orf36
Uncharacterized protein C3orf36.
   
  
 0.522
LRRC74B
Leucine-rich repeat-containing protein 74B; Leucine rich repeat containing 74B.
      
 0.470
C8orf86
Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.
      
 0.430
C10orf55
Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55.
   
  
 0.423
PAX3
Paired box protein Pax-3; Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 ; Belongs to the paired homeobox family.
   
  
 0.422
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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