STPG2 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEFB125	EFCAB10	ENSP00000371847	ENSP00000417841	Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family.	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	0.477
DEFB125	STPG2	ENSP00000371847	ENSP00000295268	Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family.	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.477
DIPK1C	STPG2	ENSP00000344331	ENSP00000295268	Divergent protein kinase domain 1C.	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.563
DNAJB14	STPG2	ENSP00000404381	ENSP00000295268	DnaJ homolog subfamily B member 14; Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum- associated degradation (ERAD) pathway. Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of na [...]	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.495
EFCAB10	DEFB125	ENSP00000417841	ENSP00000371847	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family.	0.477
EFCAB10	FAM166C	ENSP00000417841	ENSP00000332875	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	Protein FAM166C; Family with sequence similarity 166 member C; Belongs to the FAM166C family.	0.659
EFCAB10	STPG2	ENSP00000417841	ENSP00000295268	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.478
FAM166C	EFCAB10	ENSP00000332875	ENSP00000417841	Protein FAM166C; Family with sequence similarity 166 member C; Belongs to the FAM166C family.	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	0.659
FAM166C	STPG2	ENSP00000332875	ENSP00000295268	Protein FAM166C; Family with sequence similarity 166 member C; Belongs to the FAM166C family.	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.484
M1AP	STPG2	ENSP00000290536	ENSP00000295268	Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis.	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.519
METAP1	STPG2	ENSP00000296411	ENSP00000295268	Methionine aminopeptidase 1; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.490
NYX	STPG2	ENSP00000340328	ENSP00000295268	Nyctalopin.	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	0.809
STPG2	DEFB125	ENSP00000295268	ENSP00000371847	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family.	0.477
STPG2	DIPK1C	ENSP00000295268	ENSP00000344331	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	Divergent protein kinase domain 1C.	0.563
STPG2	DNAJB14	ENSP00000295268	ENSP00000404381	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	DnaJ homolog subfamily B member 14; Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum- associated degradation (ERAD) pathway. Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of na [...]	0.495
STPG2	EFCAB10	ENSP00000295268	ENSP00000417841	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	0.478
STPG2	FAM166C	ENSP00000295268	ENSP00000332875	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	Protein FAM166C; Family with sequence similarity 166 member C; Belongs to the FAM166C family.	0.484
STPG2	M1AP	ENSP00000295268	ENSP00000290536	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis.	0.519
STPG2	METAP1	ENSP00000295268	ENSP00000296411	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	Methionine aminopeptidase 1; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.	0.490
STPG2	NYX	ENSP00000295268	ENSP00000340328	Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.	Nyctalopin.	0.809