node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATF7IP2 | TMEM144 | ENSP00000379808 | ENSP00000296529 | Activating transcription factor 7-interacting protein 2; Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable); Belongs to the MCAF family. | Transmembrane protein 144; Belongs to the TMEM144 family. | 0.433 |
GASK1B | TMEM144 | ENSP00000377396 | ENSP00000296529 | Golgi associated kinase 1B; Belongs to the GASK family. | Transmembrane protein 144; Belongs to the TMEM144 family. | 0.426 |
KCTD9 | KTI12 | ENSP00000221200 | ENSP00000360676 | BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. | KTI12 chromatin associated homolog. | 0.404 |
KCTD9 | LZIC | ENSP00000221200 | ENSP00000366430 | BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. | Protein LZIC; Leucine zipper and CTNNBIP1 domain containing. | 0.487 |
KCTD9 | TMEM144 | ENSP00000221200 | ENSP00000296529 | BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. | Transmembrane protein 144; Belongs to the TMEM144 family. | 0.485 |
KTI12 | KCTD9 | ENSP00000360676 | ENSP00000221200 | KTI12 chromatin associated homolog. | BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. | 0.404 |
KTI12 | LZIC | ENSP00000360676 | ENSP00000366430 | KTI12 chromatin associated homolog. | Protein LZIC; Leucine zipper and CTNNBIP1 domain containing. | 0.546 |
KTI12 | TMEM144 | ENSP00000360676 | ENSP00000296529 | KTI12 chromatin associated homolog. | Transmembrane protein 144; Belongs to the TMEM144 family. | 0.537 |
LZIC | KCTD9 | ENSP00000366430 | ENSP00000221200 | Protein LZIC; Leucine zipper and CTNNBIP1 domain containing. | BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. | 0.487 |
LZIC | KTI12 | ENSP00000366430 | ENSP00000360676 | Protein LZIC; Leucine zipper and CTNNBIP1 domain containing. | KTI12 chromatin associated homolog. | 0.546 |
LZIC | TMEM144 | ENSP00000366430 | ENSP00000296529 | Protein LZIC; Leucine zipper and CTNNBIP1 domain containing. | Transmembrane protein 144; Belongs to the TMEM144 family. | 0.557 |
SLC30A1 | SLC35B3 | ENSP00000355968 | ENSP00000368981 | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon. | 0.476 |
SLC30A1 | SLC35C1 | ENSP00000355968 | ENSP00000313318 | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. | 0.408 |
SLC30A1 | SLC35C2 | ENSP00000355968 | ENSP00000318960 | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells. | 0.427 |
SLC30A1 | TMEM144 | ENSP00000355968 | ENSP00000296529 | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Transmembrane protein 144; Belongs to the TMEM144 family. | 0.430 |
SLC35B3 | SLC30A1 | ENSP00000368981 | ENSP00000355968 | Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon. | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.476 |
SLC35B3 | SLC35C1 | ENSP00000368981 | ENSP00000313318 | Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon. | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. | 0.717 |
SLC35B3 | SLC35C2 | ENSP00000368981 | ENSP00000318960 | Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon. | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells. | 0.666 |
SLC35B3 | TMEM144 | ENSP00000368981 | ENSP00000296529 | Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon. | Transmembrane protein 144; Belongs to the TMEM144 family. | 0.504 |
SLC35C1 | SLC30A1 | ENSP00000313318 | ENSP00000355968 | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. | Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.408 |