STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF474Zinc finger protein 474. (364 aa)    
Predicted Functional Partners:
ZNF202
Zinc finger protein 202; Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease.
    
 
 0.661
CFAP161
Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.
   
    0.545
CFAP57
Cilia and flagella associated protein 57.
   
   0.492
K7ERI5_HUMAN
KRAB domain-containing protein.
    
 
 0.480
M0R233_HUMAN
KRAB domain-containing protein.
    
 
 0.480
M0R2Z0_HUMAN
KRAB domain-containing protein.
    
 
 0.480
V9GYS6_HUMAN
KRAB domain-containing protein.
    
 
 0.480
ENSP00000481316
KRAB domain-containing protein.
    
 
 0.480
M0R1X1_HUMAN
KRAB domain-containing protein.
    
 
 0.478
ZNHIT1
Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity ; Belongs to the ZNHIT1 family.
   
    0.461
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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