Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C9orf24Spermatid-specific manchette-related protein 1; May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of ciliated cells. Belongs to the SMRP1 family. (262 aa)    
Predicted Functional Partners:
EFHC2
EF-hand domain-containing family member C2; EF-hand domain containing 2.
   
 
 0.959
RIBC1
RIB43A domain with coiled-coils 1; Belongs to the RIB43A family.
   
 
 0.958
CCDC105
Coiled-coil domain containing 105.
   
 
 0.948
EFHB
EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus.
   
 
 0.935
TEKT2
Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
   
 
 0.931
ODF3
Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.
   
 
 0.918
FAM166A
Protein FAM166A; Family with sequence similarity 166 member A.
   
 
 0.912
TEKT5
Tektin-5; May be a structural component of the sperm flagellum.
   
 
 0.911
TEPP
Testis, prostate and placenta expressed.
   
   0.898
TMCO5A
Transmembrane and coiled-coil domains 5A; Belongs to the TMCO5 family.
   
  
 0.883
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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