node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GPR137C | TCP11L2 | ENSP00000315106 | ENSP00000299045 | Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family. | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | 0.472 |
POLR3B | TCP11L2 | ENSP00000228347 | ENSP00000299045 | DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...] | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | 0.570 |
POLR3B | TMEM263 | ENSP00000228347 | ENSP00000449785 | DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...] | Transmembrane protein 263. | 0.468 |
POLR3B | TTC5 | ENSP00000228347 | ENSP00000258821 | DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...] | Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). | 0.554 |
TCP11L2 | GPR137C | ENSP00000299045 | ENSP00000315106 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family. | 0.472 |
TCP11L2 | POLR3B | ENSP00000299045 | ENSP00000228347 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...] | 0.570 |
TCP11L2 | TMEM234 | ENSP00000299045 | ENSP00000309792 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Transmembrane protein 234; Belongs to the TMEM234 family. | 0.466 |
TCP11L2 | TMEM263 | ENSP00000299045 | ENSP00000449785 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Transmembrane protein 263. | 0.558 |
TCP11L2 | TTC5 | ENSP00000299045 | ENSP00000258821 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). | 0.592 |
TCP11L2 | TUBA1A | ENSP00000299045 | ENSP00000439020 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Detyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.633 |
TCP11L2 | TUBA1B | ENSP00000299045 | ENSP00000336799 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Detyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.753 |
TCP11L2 | TUBA1C | ENSP00000299045 | ENSP00000443475 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Detyrosinated tubulin alpha-1C chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. | 0.710 |
TCP11L2 | TUBA3E | ENSP00000299045 | ENSP00000318197 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Detyrosinated tubulin alpha-3E chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family. | 0.641 |
TCP11L2 | TUBA4A | ENSP00000299045 | ENSP00000248437 | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | Tubulin alpha-4A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.581 |
TMEM234 | TCP11L2 | ENSP00000309792 | ENSP00000299045 | Transmembrane protein 234; Belongs to the TMEM234 family. | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | 0.466 |
TMEM263 | POLR3B | ENSP00000449785 | ENSP00000228347 | Transmembrane protein 263. | DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...] | 0.468 |
TMEM263 | TCP11L2 | ENSP00000449785 | ENSP00000299045 | Transmembrane protein 263. | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | 0.558 |
TTC5 | POLR3B | ENSP00000258821 | ENSP00000228347 | Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). | DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the clef [...] | 0.554 |
TTC5 | TCP11L2 | ENSP00000258821 | ENSP00000299045 | Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). | T-complex protein 11-like protein 2; T-complex 11 like 2; Belongs to the TCP11 family. | 0.592 |
TTC5 | TUBA1C | ENSP00000258821 | ENSP00000443475 | Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity). | Detyrosinated tubulin alpha-1C chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. | 0.450 |