| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKAP3 | AKAP4 | ENSP00000228850 | ENSP00000351327 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | 0.974 |
| AKAP3 | CAPZA3 | ENSP00000228850 | ENSP00000326238 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | 0.736 |
| AKAP3 | SAXO1 | ENSP00000228850 | ENSP00000369907 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Stabilizer of axonemal microtubules 1; May play a role in the regulation of cilium length. Stabilizes microtubules at low temperature. Belongs to the FAM154 family. | 0.648 |
| AKAP3 | SPATA19 | ENSP00000228850 | ENSP00000299140 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis. | 0.612 |
| AKAP3 | SUN5 | ENSP00000228850 | ENSP00000348496 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | SUN domain-containing protein 5; Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope. | 0.490 |
| AKAP3 | TCP11 | ENSP00000228850 | ENSP00000501201 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. | 0.697 |
| AKAP4 | AKAP3 | ENSP00000351327 | ENSP00000228850 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | 0.974 |
| AKAP4 | CAPZA3 | ENSP00000351327 | ENSP00000326238 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | 0.783 |
| AKAP4 | SAXO1 | ENSP00000351327 | ENSP00000369907 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | Stabilizer of axonemal microtubules 1; May play a role in the regulation of cilium length. Stabilizes microtubules at low temperature. Belongs to the FAM154 family. | 0.592 |
| AKAP4 | SPATA19 | ENSP00000351327 | ENSP00000299140 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis. | 0.679 |
| AKAP4 | SUN5 | ENSP00000351327 | ENSP00000348496 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | SUN domain-containing protein 5; Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope. | 0.539 |
| AKAP4 | TCP11 | ENSP00000351327 | ENSP00000501201 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. | 0.742 |
| AKAP4 | TNP2 | ENSP00000351327 | ENSP00000325738 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.540 |
| CAPZA3 | AKAP3 | ENSP00000326238 | ENSP00000228850 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | 0.736 |
| CAPZA3 | AKAP4 | ENSP00000326238 | ENSP00000351327 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | 0.783 |
| CAPZA3 | SPATA19 | ENSP00000326238 | ENSP00000299140 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis. | 0.590 |
| CAPZA3 | SUN5 | ENSP00000326238 | ENSP00000348496 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | SUN domain-containing protein 5; Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope. | 0.736 |
| CAPZA3 | TCP11 | ENSP00000326238 | ENSP00000501201 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. | 0.652 |
| CAPZA3 | TEX35 | ENSP00000326238 | ENSP00000323795 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Testis-expressed protein 35; Testis expressed 35. | 0.519 |
| CAPZA3 | TNP2 | ENSP00000326238 | ENSP00000325738 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.430 |
