CCDC182 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC182	CCDC89	ENSP00000299415	ENSP00000320649	Coiled-coil domain containing 182.	Coiled-coil domain containing 89; Belongs to the CCDC89 family.	0.453
CCDC182	CNTLN	ENSP00000299415	ENSP00000370021	Coiled-coil domain containing 182.	Centlein; Required for centrosome cohesion and recruitment of CEP68 to centrosomes.	0.454
CCDC182	GOLGA7B	ENSP00000299415	ENSP00000359634	Coiled-coil domain containing 182.	Golgin subfamily A member 7B; May be involved in protein transport from Golgi to cell surface; Belongs to the ERF4 family.	0.405
CCDC182	IQCF1	ENSP00000299415	ENSP00000307958	Coiled-coil domain containing 182.	IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.	0.460
CCDC182	KLHL10	ENSP00000299415	ENSP00000293303	Coiled-coil domain containing 182.	Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis.	0.415
CCDC182	MEAK7	ENSP00000299415	ENSP00000343635	Coiled-coil domain containing 182.	MTOR-associated protein MEAK7; Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome.	0.453
CCDC182	TVP23C	ENSP00000299415	ENSP00000225576	Coiled-coil domain containing 182.	Trans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family.	0.439
CCDC89	CCDC182	ENSP00000320649	ENSP00000299415	Coiled-coil domain containing 89; Belongs to the CCDC89 family.	Coiled-coil domain containing 182.	0.453
CNTLN	CCDC182	ENSP00000370021	ENSP00000299415	Centlein; Required for centrosome cohesion and recruitment of CEP68 to centrosomes.	Coiled-coil domain containing 182.	0.454
GOLGA7B	CCDC182	ENSP00000359634	ENSP00000299415	Golgin subfamily A member 7B; May be involved in protein transport from Golgi to cell surface; Belongs to the ERF4 family.	Coiled-coil domain containing 182.	0.405
GOLGA7B	MEAK7	ENSP00000359634	ENSP00000343635	Golgin subfamily A member 7B; May be involved in protein transport from Golgi to cell surface; Belongs to the ERF4 family.	MTOR-associated protein MEAK7; Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome.	0.490
IQCF1	CCDC182	ENSP00000307958	ENSP00000299415	IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.	Coiled-coil domain containing 182.	0.460
IQCF1	KLHL10	ENSP00000307958	ENSP00000293303	IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.	Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis.	0.497
KLHL10	CCDC182	ENSP00000293303	ENSP00000299415	Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis.	Coiled-coil domain containing 182.	0.415
KLHL10	IQCF1	ENSP00000293303	ENSP00000307958	Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis.	IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.	0.497
MEAK7	CCDC182	ENSP00000343635	ENSP00000299415	MTOR-associated protein MEAK7; Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome.	Coiled-coil domain containing 182.	0.453
MEAK7	GOLGA7B	ENSP00000343635	ENSP00000359634	MTOR-associated protein MEAK7; Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome.	Golgin subfamily A member 7B; May be involved in protein transport from Golgi to cell surface; Belongs to the ERF4 family.	0.490
TVP23C	CCDC182	ENSP00000225576	ENSP00000299415	Trans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family.	Coiled-coil domain containing 182.	0.439