STRINGSTRING
POTED protein (human) - STRING interaction network
"POTED" - POTE ankyrin domain family member D in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POTEDPOTE ankyrin domain family member D; Belongs to the POTE family (584 aa)    
Predicted Functional Partners:
POTEC
POTE ankyrin domain family member C (542 aa)
       
   
0.847
339010
Homo sapiens POTE ankyrin domain family, member B-like (LOC102724631), transcript variant 1, mRNA; Belongs to the POTE family (581 aa)
       
 
0.821
TMEM105
Transmembrane protein 105 (129 aa)
           
  0.477
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (301 aa)
     
 
  0.464
C4orf45
Uncharacterized protein C4orf45; Chromosome 4 open reading frame 45 (186 aa)
           
  0.448
CAP1
Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family (475 aa)
     
 
  0.441
CAP2
Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family (477 aa)
     
 
  0.441
PFN1
Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (140 aa)
       
 
  0.440
FMNL1
Formin-like protein 1; May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; Armadillo-like helical domain containing (1100 aa)
       
 
  0.433
WDR90
WD repeat-containing protein 90; WD repeat domain containing (1748 aa)
     
 
  0.432
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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