node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HAGH | LDHD | ENSP00000380514 | ENSP00000300051 | Hydroxyacylglutathione hydrolase, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Probable D-lactate dehydrogenase, mitochondrial; Involved in D-lactate, but not L-lactate catabolic process. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.933 |
LDHA | LDHAL6A | ENSP00000445175 | ENSP00000280706 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | 0.799 |
LDHA | LDHC | ENSP00000445175 | ENSP00000437783 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.985 |
LDHA | LDHD | ENSP00000445175 | ENSP00000300051 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Probable D-lactate dehydrogenase, mitochondrial; Involved in D-lactate, but not L-lactate catabolic process. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.946 |
LDHA | ME1 | ENSP00000445175 | ENSP00000358719 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Malic enzyme 1. | 0.958 |
LDHA | PDHA2 | ENSP00000445175 | ENSP00000295266 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | 0.939 |
LDHA | PDHB | ENSP00000445175 | ENSP00000307241 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | 0.961 |
LDHA | PKLR | ENSP00000445175 | ENSP00000339933 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Pyruvate kinase PKLR; Plays a key role in glycolysis. | 0.986 |
LDHA | PKM | ENSP00000445175 | ENSP00000320171 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | 0.997 |
LDHAL6A | LDHA | ENSP00000280706 | ENSP00000445175 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | 0.799 |
LDHAL6A | LDHC | ENSP00000280706 | ENSP00000437783 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.786 |
LDHAL6A | LDHD | ENSP00000280706 | ENSP00000300051 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Probable D-lactate dehydrogenase, mitochondrial; Involved in D-lactate, but not L-lactate catabolic process. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.939 |
LDHAL6A | ME1 | ENSP00000280706 | ENSP00000358719 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Malic enzyme 1. | 0.954 |
LDHAL6A | PDHA2 | ENSP00000280706 | ENSP00000295266 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | 0.923 |
LDHAL6A | PDHB | ENSP00000280706 | ENSP00000307241 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | 0.944 |
LDHAL6A | PKLR | ENSP00000280706 | ENSP00000339933 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Pyruvate kinase PKLR; Plays a key role in glycolysis. | 0.986 |
LDHAL6A | PKM | ENSP00000280706 | ENSP00000320171 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | 0.986 |
LDHAL6B | LDHD | ENSP00000302393 | ENSP00000300051 | Lactate dehydrogenase A like 6B. | Probable D-lactate dehydrogenase, mitochondrial; Involved in D-lactate, but not L-lactate catabolic process. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.966 |
LDHAL6B | ME1 | ENSP00000302393 | ENSP00000358719 | Lactate dehydrogenase A like 6B. | Malic enzyme 1. | 0.954 |
LDHAL6B | PDHA2 | ENSP00000302393 | ENSP00000295266 | Lactate dehydrogenase A like 6B. | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | 0.927 |