C16orf92 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPHD1	C16orf54	ENSP00000311447	ENSP00000327506	Aspartate beta-hydroxylase domain containing 1.	Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.	0.774
ASPHD1	C16orf92	ENSP00000311447	ENSP00000300575	Aspartate beta-hydroxylase domain containing 1.	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	0.621
ASPHD1	DOC2A	ENSP00000311447	ENSP00000482870	Aspartate beta-hydroxylase domain containing 1.	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.	0.665
ASPHD1	HIRIP3	ENSP00000311447	ENSP00000279392	Aspartate beta-hydroxylase domain containing 1.	HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.	0.683
ASPHD1	YPEL3	ENSP00000311447	ENSP00000381821	Aspartate beta-hydroxylase domain containing 1.	Protein yippee-like 3; Involved in proliferation and apoptosis in myeloid precursor cells.	0.673
C16orf54	ASPHD1	ENSP00000327506	ENSP00000311447	Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.	Aspartate beta-hydroxylase domain containing 1.	0.774
C16orf54	C16orf92	ENSP00000327506	ENSP00000300575	Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	0.622
C16orf54	DOC2A	ENSP00000327506	ENSP00000482870	Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.	0.570
C16orf54	HIRIP3	ENSP00000327506	ENSP00000279392	Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.	HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.	0.621
C16orf54	YPEL3	ENSP00000327506	ENSP00000381821	Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.	Protein yippee-like 3; Involved in proliferation and apoptosis in myeloid precursor cells.	0.666
C16orf92	ASPHD1	ENSP00000300575	ENSP00000311447	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	Aspartate beta-hydroxylase domain containing 1.	0.621
C16orf92	C16orf54	ENSP00000300575	ENSP00000327506	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.	0.622
C16orf92	DCST1	ENSP00000300575	ENSP00000295542	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	E3 ubiquitin-protein ligase DCST1; E3 ubiquitin-protein ligase which mediates 'Lys-48'-linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling.	0.663
C16orf92	DCST2	ENSP00000300575	ENSP00000357409	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	DC-STAMP domain containing 2.	0.701
C16orf92	DOC2A	ENSP00000300575	ENSP00000482870	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.	0.584
C16orf92	HIRIP3	ENSP00000300575	ENSP00000279392	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.	0.548
C16orf92	IZUMO1	ENSP00000300575	ENSP00000327786	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand- receptor interaction probably does not act as a membrane 'fusogen'.	0.676
C16orf92	SPACA6	ENSP00000300575	ENSP00000490829	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	Sperm acrosome membrane-associated protein 6; Sperm protein potentially involved sperm-egg fusion.	0.752
C16orf92	TMEM95	ENSP00000300575	ENSP00000374632	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	Transmembrane protein 95.	0.776
C16orf92	YPEL3	ENSP00000300575	ENSP00000381821	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92.	Protein yippee-like 3; Involved in proliferation and apoptosis in myeloid precursor cells.	0.550