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HDHD2 protein (human) - STRING interaction network
"HDHD2" - Haloacid dehalogenase like hydrolase domain containing 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDHD2Haloacid dehalogenase like hydrolase domain containing 2 (259 aa)    
Predicted Functional Partners:
IER3IP1
Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) (82 aa)
 
 
   
  0.792
SKOR2
SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors (1015 aa)
           
  0.703
TBC1D12
TBC1 domain family member 12; May act as a GTPase-activating protein for Rab family protein(s) (775 aa)
     
   
  0.682
DCTN5
Dynactin subunit 5; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily (182 aa)
 
 
        0.661
ST8SIA5
Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively; Belongs to the glycosyltransferase 29 family (376 aa)
           
  0.656
NOC3L
Nucleolar complex protein 3 homolog; May be required for adipogenesis; Armadillo-like helical domain containing (800 aa)
     
   
  0.654
TMED4
Transmembrane emp24 domain-containing protein 4; Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity); Transmembrane p24 trafficking proteins (227 aa)
     
   
  0.646
LSM14A
Protein LSM14 homolog A; Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs; LSm proteins (463 aa)
     
   
  0.628
TTC38
Tetratricopeptide repeat domain containing; Belongs to the TTC38 family (469 aa)
           
  0.615
TCOF1
Treacle protein; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification- following monoubiquitination by the BCR(KBTBD8) complex, associates with NOLC1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (1488 aa)
           
  0.598
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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