node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCK5 | LRRC14 | ENSP00000310547 | ENSP00000292524 | Uncharacterized aarF domain-containing protein kinase 5; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | 0.580 |
ADCK5 | MFSD3 | ENSP00000310547 | ENSP00000301327 | Uncharacterized aarF domain-containing protein kinase 5; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). | Major facilitator superfamily domain containing 3. | 0.649 |
ADCK5 | PPP1R16A | ENSP00000310547 | ENSP00000292539 | Uncharacterized aarF domain-containing protein kinase 5; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). | Protein phosphatase 1 regulatory subunit 16A; Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates. | 0.552 |
LRRC14 | ADCK5 | ENSP00000292524 | ENSP00000310547 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | Uncharacterized aarF domain-containing protein kinase 5; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). | 0.580 |
LRRC14 | MFSD3 | ENSP00000292524 | ENSP00000301327 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | Major facilitator superfamily domain containing 3. | 0.601 |
LRRC14 | PPP1R16A | ENSP00000292524 | ENSP00000292539 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | Protein phosphatase 1 regulatory subunit 16A; Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates. | 0.628 |
MFSD10 | MFSD11 | ENSP00000332646 | ENSP00000464932 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | 0.624 |
MFSD10 | MFSD14A | ENSP00000332646 | ENSP00000359171 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | Hippocampus abundant transcript 1 protein; Major facilitator superfamily domain containing 14A. | 0.462 |
MFSD10 | MFSD2B | ENSP00000332646 | ENSP00000342501 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | Major facilitator superfamily domain-containing protein 2B; Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology (By similarity). Does not transport lysophosphatidylcholine (LPC) (By similarity). Belongs to the major facilitator superfamily. | 0.513 |
MFSD10 | MFSD3 | ENSP00000332646 | ENSP00000301327 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | Major facilitator superfamily domain containing 3. | 0.600 |
MFSD10 | MFSD5 | ENSP00000332646 | ENSP00000442688 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily. | 0.653 |
MFSD10 | MFSD9 | ENSP00000332646 | ENSP00000258436 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | Major facilitator superfamily domain containing 9. | 0.577 |
MFSD10 | SPNS3 | ENSP00000332646 | ENSP00000347721 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | Protein spinster homolog 3; Sphingolipid transporter. | 0.615 |
MFSD11 | MFSD10 | ENSP00000464932 | ENSP00000332646 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump; Belongs to the major facilitator superfamily. | 0.624 |
MFSD11 | MFSD14A | ENSP00000464932 | ENSP00000359171 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | Hippocampus abundant transcript 1 protein; Major facilitator superfamily domain containing 14A. | 0.543 |
MFSD11 | MFSD2B | ENSP00000464932 | ENSP00000342501 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | Major facilitator superfamily domain-containing protein 2B; Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology (By similarity). Does not transport lysophosphatidylcholine (LPC) (By similarity). Belongs to the major facilitator superfamily. | 0.520 |
MFSD11 | MFSD3 | ENSP00000464932 | ENSP00000301327 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | Major facilitator superfamily domain containing 3. | 0.645 |
MFSD11 | MFSD5 | ENSP00000464932 | ENSP00000442688 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily. | 0.784 |
MFSD11 | MFSD9 | ENSP00000464932 | ENSP00000258436 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | Major facilitator superfamily domain containing 9. | 0.688 |
MFSD11 | SPNS3 | ENSP00000464932 | ENSP00000347721 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family. | Protein spinster homolog 3; Sphingolipid transporter. | 0.548 |