STRINGSTRING
GPR25 protein (human) - STRING interaction network
"GPR25" - G protein-coupled receptor 25 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR25G protein-coupled receptor 25; Orphan receptor (361 aa)    
Predicted Functional Partners:
GPR27
G protein-coupled receptor 27; Orphan receptor. Possible candidate for amine-like G- protein coupled receptor (375 aa)
         
  0.935
GPR20
G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP (358 aa)
     
 
  0.928
GPR150
G protein-coupled receptor 150; Orphan receptor (434 aa)
     
 
  0.922
GPR15
G protein-coupled receptor 15; Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection (360 aa)
     
 
0.918
GPR45
G protein-coupled receptor 45; Orphan receptor. May play a role in brain function (372 aa)
     
 
  0.913
GNG5
Guanine nucleotide binding protein (G protein), gamma 5; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (68 aa)
         
  0.911
GPR176
G protein-coupled receptor 176; Orphan receptor (515 aa)
         
  0.910
GPR32
G protein-coupled receptor 32; Orphan receptor (356 aa)
         
0.910
GPR84
G protein-coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10-0), undecanoic acid (C11-0) and lauric acid (C12-0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system (396 aa)
         
  0.905
ADORA2A
Adenosine A2a receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (412 aa)
     
 
  0.904
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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