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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF280AZinc finger protein 280A; May function as a transcription factor. (542 aa)    
Predicted Functional Partners:
PRAME
Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
   
  
 0.669
POM121L1P
Putative POM121-like protein 1.
      
 0.624
GGTLC2
Gamma-glutamyltransferase light chain 2; Belongs to the gamma-glutamyltransferase family.
   
  
 0.621
IQANK1
IQ motif and ankyrin repeat containing 1.
    
 
 0.601
ZNF200
Zinc finger protein 200; Could have a role in spermatogenesis.
      
 0.595
ZNF668
Zinc finger protein 668; May be involved in transcriptional regulation.
    
 
 0.566
ZNF382
Zinc finger protein 382; Functions as a sequence-specific transcriptional repressor. Belongs to the krueppel C2H2-type zinc-finger protein family.
   
 
 0.516
OR1L3
Olfactory receptor 1L3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.506
ZNF84
Zinc finger protein 84; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
 
0.506
OR1L1
Olfactory receptor 1L1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.495
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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