Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C7orf33Uncharacterized protein C7orf33; Chromosome 7 open reading frame 33. (177 aa)    
Predicted Functional Partners:
TNNC2
Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
    
   0.565
GIMAP1-GIMAP5
GIMAP1-GIMAP5 readthrough.
      
 0.497
ZNF425
Zinc finger protein 425; Acts as a transcriptional repressor.
      
 0.481
ZNF786
Zinc finger protein 786; May be involved in transcriptional regulation.
   
  
 0.481
IQCA1L
IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.
      
 0.466
ZNF783
Protein ZNF783; May be involved in transcriptional regulation.
      
 0.444
ZBED6CL
ZBED6 C-terminal-like protein; ZBED6 C-terminal like.
      
 0.441
WDR86
WD repeat domain 86.
      
 0.441
LRRC61
Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61.
      
 0.439
KRBA1
Protein KRBA1; KRAB-A domain containing 1.
      
 0.429
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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