PPDPFL protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GOLGA6L7	PPDPFL	ENSP00000490318	ENSP00000304926	Golgin subfamily A member 6-like protein 7; Golgin A6 family like 7; Belongs to the GOLGA6 family.	Pancreatic progenitor cell differentiation and proliferation factor like.	0.425
GOLGA6L7	PRR30	ENSP00000490318	ENSP00000335017	Golgin subfamily A member 6-like protein 7; Golgin A6 family like 7; Belongs to the GOLGA6 family.	Proline-rich protein 30; Proline rich 30.	0.445
LYPD2	PPDPFL	ENSP00000352163	ENSP00000304926	LY6/PLAUR domain containing 2.	Pancreatic progenitor cell differentiation and proliferation factor like.	0.419
NAT16	PPDPFL	ENSP00000300303	ENSP00000304926	Probable N-acetyltransferase 16; Probable N-acetyltransferase. Shows only trace activity toward L-His and no N-acetyltransferase activity toward other amino acids. The physiological substrate of this enzyme is unknown.	Pancreatic progenitor cell differentiation and proliferation factor like.	0.408
NAT8L	PPDPFL	ENSP00000413064	ENSP00000304926	N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N- acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.	Pancreatic progenitor cell differentiation and proliferation factor like.	0.454
NKX6-3	PPDPFL	ENSP00000429553	ENSP00000304926	Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.	Pancreatic progenitor cell differentiation and proliferation factor like.	0.423
PALM2AKAP2	PPDPFL	ENSP00000363654	ENSP00000304926	A-kinase anchor protein 2; Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).	Pancreatic progenitor cell differentiation and proliferation factor like.	0.443
PPDPFL	GOLGA6L7	ENSP00000304926	ENSP00000490318	Pancreatic progenitor cell differentiation and proliferation factor like.	Golgin subfamily A member 6-like protein 7; Golgin A6 family like 7; Belongs to the GOLGA6 family.	0.425
PPDPFL	LYPD2	ENSP00000304926	ENSP00000352163	Pancreatic progenitor cell differentiation and proliferation factor like.	LY6/PLAUR domain containing 2.	0.419
PPDPFL	NAT16	ENSP00000304926	ENSP00000300303	Pancreatic progenitor cell differentiation and proliferation factor like.	Probable N-acetyltransferase 16; Probable N-acetyltransferase. Shows only trace activity toward L-His and no N-acetyltransferase activity toward other amino acids. The physiological substrate of this enzyme is unknown.	0.408
PPDPFL	NAT8L	ENSP00000304926	ENSP00000413064	Pancreatic progenitor cell differentiation and proliferation factor like.	N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N- acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.	0.454
PPDPFL	NKX6-3	ENSP00000304926	ENSP00000429553	Pancreatic progenitor cell differentiation and proliferation factor like.	Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.	0.423
PPDPFL	PALM2AKAP2	ENSP00000304926	ENSP00000363654	Pancreatic progenitor cell differentiation and proliferation factor like.	A-kinase anchor protein 2; Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).	0.443
PPDPFL	PRR30	ENSP00000304926	ENSP00000335017	Pancreatic progenitor cell differentiation and proliferation factor like.	Proline-rich protein 30; Proline rich 30.	0.510
PRR30	GOLGA6L7	ENSP00000335017	ENSP00000490318	Proline-rich protein 30; Proline rich 30.	Golgin subfamily A member 6-like protein 7; Golgin A6 family like 7; Belongs to the GOLGA6 family.	0.445
PRR30	PPDPFL	ENSP00000335017	ENSP00000304926	Proline-rich protein 30; Proline rich 30.	Pancreatic progenitor cell differentiation and proliferation factor like.	0.510