STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT28Keratin, type I cytoskeletal 28; Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs). (464 aa)    
Predicted Functional Partners:
KRT25
Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization.
  
 
0.582
KRT38
Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family.
  
 
0.506
KRT27
Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs).
  
0.501
KRT35
Keratin, type I cuticular Ha5; Keratin 35; Belongs to the intermediate filament family.
  
 
0.495
KRT33A
Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family.
  
 
0.490
KRT31
Keratin, type I cuticular Ha1; Keratin 31.
  
 
0.489
KRT26
Keratin, type I cytoskeletal 26; Keratin 26.
  
 
0.484
KRT39
Keratin, type I cytoskeletal 39; May play a role in late hair differentiation.
  
 
0.483
KRT40
Keratin, type I cytoskeletal 40; May play a role in late hair differentiation; Belongs to the intermediate filament family.
  
 
0.482
KRT37
Keratin, type I cuticular Ha7; Keratin 37.
  
 
0.481
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.