STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM71BProtein FAM71B; May be involved in RNA biogenesis. (605 aa)    
Predicted Functional Partners:
FAM205A
Protein FAM205A; Family with sequence similarity 205 member A.
   
  
 0.578
SPEM3
Uncharacterized protein SPEM3; SPEM family member 3.
      
 0.576
MORN5
MORN repeat containing 5.
   
  
 0.529
CCDC136
Coiled-coil domain-containing protein 136; May play a role in acrosome formation in spermatogenesis and in fertilization.
  
  
 0.523
C6orf118
Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118.
      
 0.507
PPP1R2B
Protein phosphatase inhibitor 2 family member B; Inhibitor of protein-phosphatase 1.
      
 0.507
ALMS1
Alstrom syndrome protein 1; Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells.
  
  
 0.467
PROCA1
Protein interacting with cyclin A1; Belongs to the PROCA1 family.
   
  
 0.464
SPATA3
Spermatogenesis-associated protein 3; Spermatogenesis associated 3.
   
  
 0.461
LELP1
Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family.
   
  
 0.455
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.