FAM71B protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFHC2	FAM205A	ENSP00000404232	ENSP00000417711	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Protein FAM205A; Family with sequence similarity 205 member A.	0.552
EFHC2	FAM71B	ENSP00000404232	ENSP00000305596	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Protein FAM71B; May be involved in RNA biogenesis.	0.731
EFHC2	LRRC37B	ENSP00000404232	ENSP00000340519	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Leucine-rich repeat-containing protein 37B; Leucine rich repeat containing 37B.	0.482
EFHC2	NT5C1B	ENSP00000404232	ENSP00000352904	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Cytosolic 5'-nucleotidase 1B; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity).	0.595
EFHC2	ODF3	ENSP00000404232	ENSP00000325868	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.	0.798
EFHC2	PACRG	ENSP00000404232	ENSP00000337946	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.	0.968
EFHC2	ROPN1	ENSP00000404232	ENSP00000184183	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family.	0.526
EFHC2	SPACA1	ENSP00000404232	ENSP00000237201	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis (By similarity). Important for male fertility.	0.615
EFHC2	SUN5	ENSP00000404232	ENSP00000348496	EF-hand domain-containing family member C2; EF-hand domain containing 2.	SUN domain-containing protein 5; Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.	0.479
EFHC2	TEKT2	ENSP00000404232	ENSP00000207457	EF-hand domain-containing family member C2; EF-hand domain containing 2.	Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.	0.990
FAM205A	EFHC2	ENSP00000417711	ENSP00000404232	Protein FAM205A; Family with sequence similarity 205 member A.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.552
FAM205A	FAM71B	ENSP00000417711	ENSP00000305596	Protein FAM205A; Family with sequence similarity 205 member A.	Protein FAM71B; May be involved in RNA biogenesis.	0.780
FAM205A	LRRC37B	ENSP00000417711	ENSP00000340519	Protein FAM205A; Family with sequence similarity 205 member A.	Leucine-rich repeat-containing protein 37B; Leucine rich repeat containing 37B.	0.558
FAM205A	NT5C1B	ENSP00000417711	ENSP00000352904	Protein FAM205A; Family with sequence similarity 205 member A.	Cytosolic 5'-nucleotidase 1B; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity).	0.740
FAM205A	ROPN1	ENSP00000417711	ENSP00000184183	Protein FAM205A; Family with sequence similarity 205 member A.	Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family.	0.525
FAM205A	SPACA1	ENSP00000417711	ENSP00000237201	Protein FAM205A; Family with sequence similarity 205 member A.	Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis (By similarity). Important for male fertility.	0.723
FAM205A	SUN5	ENSP00000417711	ENSP00000348496	Protein FAM205A; Family with sequence similarity 205 member A.	SUN domain-containing protein 5; Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.	0.652
FAM205A	TEKT2	ENSP00000417711	ENSP00000207457	Protein FAM205A; Family with sequence similarity 205 member A.	Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.	0.577
FAM71B	EFHC2	ENSP00000305596	ENSP00000404232	Protein FAM71B; May be involved in RNA biogenesis.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.731
FAM71B	FAM205A	ENSP00000305596	ENSP00000417711	Protein FAM71B; May be involved in RNA biogenesis.	Protein FAM205A; Family with sequence similarity 205 member A.	0.780