RBFA protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

RBFA

Putative ribosome-binding factor A, mitochondrial; Ribosome binding factor A. (343 aa)

Predicted Functional Partners:

METTL15

0.957

TFB1M

0.919

MTIF3

0.917

MRPS21

0.916

MRPS7

0.913

MRPS11

0.907

METTL17

0.886

MRPS34

0.870

MRPS25

0.869

PTCD3

0.865

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
METTL15	METTL17	ENSP00000384369	ENSP00000372445	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	0.789
METTL15	MRPS11	ENSP00000384369	ENSP00000317376	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S11.	0.878
METTL15	MRPS21	ENSP00000384369	ENSP00000461930	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.	0.833
METTL15	MRPS25	ENSP00000384369	ENSP00000253686	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S25.	0.835
METTL15	MRPS34	ENSP00000384369	ENSP00000177742	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	28S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation. Belongs to the mitochondrion-specific ribosomal protein mS34 family.	0.866
METTL15	MRPS7	ENSP00000384369	ENSP00000245539	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S7.	0.883
METTL15	PTCD3	ENSP00000384369	ENSP00000254630	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation.	0.869
METTL15	RBFA	ENSP00000384369	ENSP00000305696	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Putative ribosome-binding factor A, mitochondrial; Ribosome binding factor A.	0.957
METTL15	TFB1M	ENSP00000384369	ENSP00000356134	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Dimethyladenosine transferase 1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.	0.669
METTL17	METTL15	ENSP00000372445	ENSP00000384369	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	0.789
METTL17	MRPS11	ENSP00000372445	ENSP00000317376	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Mitochondrial ribosomal protein S11.	0.949
METTL17	MRPS21	ENSP00000372445	ENSP00000461930	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Mitochondrial ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.	0.814
METTL17	MRPS25	ENSP00000372445	ENSP00000253686	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Mitochondrial ribosomal protein S25.	0.896
METTL17	MRPS34	ENSP00000372445	ENSP00000177742	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	28S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation. Belongs to the mitochondrion-specific ribosomal protein mS34 family.	0.885
METTL17	MRPS7	ENSP00000372445	ENSP00000245539	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Mitochondrial ribosomal protein S7.	0.986
METTL17	PTCD3	ENSP00000372445	ENSP00000254630	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation.	0.857
METTL17	RBFA	ENSP00000372445	ENSP00000305696	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Putative ribosome-binding factor A, mitochondrial; Ribosome binding factor A.	0.886
METTL17	TFB1M	ENSP00000372445	ENSP00000356134	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	Dimethyladenosine transferase 1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.	0.944
MRPS11	METTL15	ENSP00000317376	ENSP00000384369	Mitochondrial ribosomal protein S11.	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	0.878
MRPS11	METTL17	ENSP00000317376	ENSP00000372445	Mitochondrial ribosomal protein S11.	Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.	0.949