RBFA protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
METTL15	MRPS11	ENSP00000384369	ENSP00000317376	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S11.	0.933
METTL15	MRPS12	ENSP00000384369	ENSP00000384952	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S12.	0.851
METTL15	MRPS18C	ENSP00000384369	ENSP00000295491	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S18C.	0.825
METTL15	MRPS5	ENSP00000384369	ENSP00000272418	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.859
METTL15	MRPS7	ENSP00000384369	ENSP00000245539	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Mitochondrial ribosomal protein S7.	0.933
METTL15	MTIF2	ENSP00000384369	ENSP00000263629	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.854
METTL15	NOA1	ENSP00000384369	ENSP00000264230	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Nitric oxide-associated protein 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP; Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily.	0.884
METTL15	RBFA	ENSP00000384369	ENSP00000305696	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Putative ribosome-binding factor A, mitochondrial; Ribosome binding factor A.	0.966
METTL15	TFB1M	ENSP00000384369	ENSP00000356134	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	Dimethyladenosine transferase 1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.	0.652
MRPS11	METTL15	ENSP00000317376	ENSP00000384369	Mitochondrial ribosomal protein S11.	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	0.933
MRPS11	MRPS12	ENSP00000317376	ENSP00000384952	Mitochondrial ribosomal protein S11.	Mitochondrial ribosomal protein S12.	0.999
MRPS11	MRPS18C	ENSP00000317376	ENSP00000295491	Mitochondrial ribosomal protein S11.	Mitochondrial ribosomal protein S18C.	0.999
MRPS11	MRPS5	ENSP00000317376	ENSP00000272418	Mitochondrial ribosomal protein S11.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.999
MRPS11	MRPS7	ENSP00000317376	ENSP00000245539	Mitochondrial ribosomal protein S11.	Mitochondrial ribosomal protein S7.	0.999
MRPS11	MTIF2	ENSP00000317376	ENSP00000263629	Mitochondrial ribosomal protein S11.	Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.971
MRPS11	NOA1	ENSP00000317376	ENSP00000264230	Mitochondrial ribosomal protein S11.	Nitric oxide-associated protein 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP; Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily.	0.930
MRPS11	RBFA	ENSP00000317376	ENSP00000305696	Mitochondrial ribosomal protein S11.	Putative ribosome-binding factor A, mitochondrial; Ribosome binding factor A.	0.908
MRPS11	TFB1M	ENSP00000317376	ENSP00000356134	Mitochondrial ribosomal protein S11.	Dimethyladenosine transferase 1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.	0.890
MRPS12	METTL15	ENSP00000384952	ENSP00000384369	Mitochondrial ribosomal protein S12.	Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.	0.851
MRPS12	MRPS11	ENSP00000384952	ENSP00000317376	Mitochondrial ribosomal protein S12.	Mitochondrial ribosomal protein S11.	0.999