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COL8A2 protein (human) - STRING interaction network
"COL8A2" - Collagen, type VIII, alpha 2 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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COL8A2Collagen, type VIII, alpha 2; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity) (703 aa)    
Predicted Functional Partners:
COL8A1
Collagen, type VIII, alpha 1; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (744 aa)
 
 
0.954
COL5A1
Collagen, type V, alpha 1; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin (1838 aa)
     
  0.940
COL4A2
Collagen, type IV, alpha 2; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1712 aa)
     
  0.928
COL4A3
Collagen, type IV, alpha 3 (Goodpasture antigen); Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1670 aa)
         
0.925
COL15A1
Collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle (1388 aa)
         
  0.924
COL3A1
Collagen, type III, alpha 1; Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12 (1466 aa)
     
 
  0.924
COL4A4
Collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1690 aa)
         
  0.924
COL4A5
Collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1691 aa)
     
 
0.923
COL12A1
Collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (3063 aa)
     
 
  0.922
COL1A2
Collagen, type I, alpha 2; Type I collagen is a member of group I collagen (fibrillar forming collagen) (1366 aa)
     
 
  0.922
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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