node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CALB2 | CCK | ENSP00000307508 | ENSP00000379472 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | 0.800 |
CALB2 | CHAT | ENSP00000307508 | ENSP00000337103 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses; Belongs to the carnitine/choline acetyltransferase family | 0.776 |
CALB2 | GAD1 | ENSP00000307508 | ENSP00000350928 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 0.859 |
CALB2 | GAD2 | ENSP00000307508 | ENSP00000365437 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Glutamate decarboxylase 2; Catalyzes the production of GABA | 0.792 |
CALB2 | NPY | ENSP00000307508 | ENSP00000384364 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Pro-neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family | 0.846 |
CALB2 | PVALB | ENSP00000307508 | ENSP00000216200 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; EF-hand domain containing | 0.948 |
CALB2 | RBFOX3 | ENSP00000307508 | ENSP00000463653 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | RNA binding protein fox-1 homolog 3; Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD); RNA binding motif containing | 0.774 |
CALB2 | SST | ENSP00000307508 | ENSP00000287641 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Somatostatin; Somatostatin inhibits the release of somatotropin; Endogenous ligands | 0.869 |
CALB2 | TH | ENSP00000307508 | ENSP00000370571 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family | 0.798 |
CALB2 | WT1 | ENSP00000307508 | ENSP00000331327 | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | Wilms tumor protein; Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has [...] | 0.776 |
CCK | CALB2 | ENSP00000379472 | ENSP00000307508 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | 0.800 |
CCK | CHAT | ENSP00000379472 | ENSP00000337103 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses; Belongs to the carnitine/choline acetyltransferase family | 0.518 |
CCK | GAD1 | ENSP00000379472 | ENSP00000350928 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 0.680 |
CCK | GAD2 | ENSP00000379472 | ENSP00000365437 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Glutamate decarboxylase 2; Catalyzes the production of GABA | 0.710 |
CCK | NPY | ENSP00000379472 | ENSP00000384364 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Pro-neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family | 0.928 |
CCK | PVALB | ENSP00000379472 | ENSP00000216200 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; EF-hand domain containing | 0.894 |
CCK | RBFOX3 | ENSP00000379472 | ENSP00000463653 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | RNA binding protein fox-1 homolog 3; Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD); RNA binding motif containing | 0.464 |
CCK | SST | ENSP00000379472 | ENSP00000287641 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Somatostatin; Somatostatin inhibits the release of somatotropin; Endogenous ligands | 0.917 |
CCK | TH | ENSP00000379472 | ENSP00000370571 | Cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Endogenous ligands | Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family | 0.636 |
CHAT | CALB2 | ENSP00000337103 | ENSP00000307508 | Choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses; Belongs to the carnitine/choline acetyltransferase family | Calbindin 2; Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons; EF-hand domain containing | 0.776 |