MT1E protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

MT1E

Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (127 aa)

Predicted Functional Partners:

MT1H

0.979

MT1G

0.979

MT1M

0.925

MT2A

0.922

MTF1

0.885

MT3

0.874

MT1X

0.867

MT1F

0.860

TESMIN

0.854

MT1HL1

0.822

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MT1E	MT1F	ENSP00000328137	ENSP00000334872	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.860
MT1E	MT1G	ENSP00000328137	ENSP00000369139	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein-1G; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.	0.979
MT1E	MT1H	ENSP00000328137	ENSP00000330587	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein-1H; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.979
MT1E	MT1HL1	ENSP00000328137	ENSP00000476141	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein 1H-like protein 1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.822
MT1E	MT1M	ENSP00000328137	ENSP00000369146	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein-1M; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.	0.925
MT1E	MT1X	ENSP00000328137	ENSP00000377995	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein-1X; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling.	0.867
MT1E	MT2A	ENSP00000328137	ENSP00000245185	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.922
MT1E	MT3	ENSP00000328137	ENSP00000200691	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.	0.874
MT1E	MTF1	ENSP00000328137	ENSP00000362127	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metal regulatory transcription factor 1; Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).	0.885
MT1E	TESMIN	ENSP00000328137	ENSP00000255087	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Tesmin; May have a role in spermatogenesis; Belongs to the lin-54 family.	0.854
MT1F	MT1E	ENSP00000334872	ENSP00000328137	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.860
MT1F	MT1G	ENSP00000334872	ENSP00000369139	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metallothionein-1G; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.	0.868
MT1F	MT1H	ENSP00000334872	ENSP00000330587	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metallothionein-1H; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.980
MT1F	MT1HL1	ENSP00000334872	ENSP00000476141	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metallothionein 1H-like protein 1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.682
MT1F	MT1M	ENSP00000334872	ENSP00000369146	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metallothionein-1M; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.	0.851
MT1F	MT1X	ENSP00000334872	ENSP00000377995	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metallothionein-1X; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling.	0.970
MT1F	MT2A	ENSP00000334872	ENSP00000245185	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.745
MT1F	MTF1	ENSP00000334872	ENSP00000362127	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Metal regulatory transcription factor 1; Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).	0.461
MT1G	MT1E	ENSP00000369139	ENSP00000328137	Metallothionein-1G; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.979
MT1G	MT1F	ENSP00000369139	ENSP00000334872	Metallothionein-1G; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.	Metallothionein-1F; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.868