STRINGSTRING
GPR171 protein (human) - STRING interaction network
"GPR171" - Probable G-protein coupled receptor 171 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GPR171Probable G-protein coupled receptor 171; Orphan receptor; G protein-coupled receptors, Class A orphans (319 aa)    
Predicted Functional Partners:
OR56B4
Olfactory receptor 56B4; Odorant receptor; Olfactory receptors, family 56 (319 aa)
           
  0.657
OR52W1
Olfactory receptor 52W1; Odorant receptor; Olfactory receptors, family 52 (320 aa)
           
  0.649
OR56A3
Olfactory receptor 56A3; Odorant receptor; Olfactory receptors, family 56 (315 aa)
           
  0.647
OR52B2
Olfactory receptor 52B2; Odorant receptor; Olfactory receptors, family 52 (323 aa)
           
  0.644
OR56A1
Olfactory receptor 56A1; Odorant receptor; Olfactory receptors, family 56 (318 aa)
           
  0.627
OR56A4
Olfactory receptor 56A4; Odorant receptor; Olfactory receptors, family 56 (365 aa)
           
  0.598
CNGA4
Cyclic nucleotide-gated cation channel alpha-4; Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity) (575 aa)
           
  0.594
GABBR1
Gamma-aminobutyric acid type B receptor subunit 1; Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-depend [...] (961 aa)
           
  0.592
GPR88
Probable G-protein coupled receptor 88; Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function (384 aa)
           
  0.565
JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an argi [...] (414 aa)
           
  0.552
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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