STRINGSTRING
RCE1 protein (human) - STRING interaction network
RCE1 homolog, prenyl protein protease (S. cerevisiae) in Homo sapiens
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RCE1RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (PubMed-10085068) (329 aa)    
Predicted Functional Partners:
ICMT
Isoprenylcysteine carboxyl methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues (284 aa)
     
  0.991
USP17L2
Ubiquitin specific peptidase 17-like family member 2; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Regulates cell proliferation by deubiquitinating and inhibiting RCE1 thereby controlling the small GTPases NRAS and HRAS localization and activation. In parallel, mediates deubiquitination of CDC25A, preventing CDC25A degradation by the proteasome during the G1/S and G2/M phases promoting cell-cycle progression. Also regulates cell proliferation and apoptosis through deubiquitination of SUDS3 a regulator of hist [...] (530 aa)
         
  0.962
FNTB
Farnesyltransferase, CAAX box, beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C- terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X (437 aa)
     
  0.954
USP17L5
Ubiquitin specific peptidase 17-like family member 5; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
         
  0.947
ENSG00000254673
Uncharacterized protein (207 aa)
     
 
  0.945
USP17L20
Ubiquitin specific peptidase 17-like family member 20; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
         
  0.934
USP17L19
Ubiquitin specific peptidase 17-like family member 19; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
         
  0.934
USP17L18
Ubiquitin specific peptidase 17-like family member 18; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
         
  0.934
USP17L22
Ubiquitin specific peptidase 17-like family member 22; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
         
  0.934
USP17L17
Ubiquitin specific peptidase 17-like family member 17; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
         
  0.934
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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