EIF1AD protein (human) - STRING interaction network

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Score

EIF1AD

Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation. (165 aa)

Predicted Functional Partners:

RIOK1

0.977

LRRC47

0.926

FAU

0.920

RPS15

0.902

RPS18

0.900

NOB1

0.873

RPS23

0.854

RPS21

0.851

RPS9

0.848

RPS2

0.842

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF1AD	FAU	ENSP00000434056	ENSP00000431822	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	0.920
EIF1AD	LRRC47	ENSP00000434056	ENSP00000367498	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	Leucine-rich repeat-containing protein 47; Leucine rich repeat containing 47.	0.926
EIF1AD	NOB1	ENSP00000434056	ENSP00000268802	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	RNA-binding protein NOB1; May play a role in mRNA degradation (Probable). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity); Belongs to the NOB1 family.	0.873
EIF1AD	RIOK1	ENSP00000434056	ENSP00000369162	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	Serine/threonine-protein kinase RIO1; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its dynamic associa [...]	0.977
EIF1AD	RPS15	ENSP00000434056	ENSP00000466010	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	Ribosomal protein S15.	0.902
EIF1AD	RPS18	ENSP00000434056	ENSP00000393241	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.	0.900
EIF1AD	RPS2	ENSP00000434056	ENSP00000341885	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	Ribosomal protein S2.	0.842
EIF1AD	RPS21	ENSP00000434056	ENSP00000345957	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.	0.851
EIF1AD	RPS23	ENSP00000434056	ENSP00000296674	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.854
EIF1AD	RPS9	ENSP00000434056	ENSP00000375632	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	Ribosomal protein S9.	0.848
FAU	EIF1AD	ENSP00000431822	ENSP00000434056	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation.	0.920
FAU	LRRC47	ENSP00000431822	ENSP00000367498	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Leucine-rich repeat-containing protein 47; Leucine rich repeat containing 47.	0.834
FAU	NOB1	ENSP00000431822	ENSP00000268802	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	RNA-binding protein NOB1; May play a role in mRNA degradation (Probable). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity); Belongs to the NOB1 family.	0.978
FAU	RIOK1	ENSP00000431822	ENSP00000369162	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Serine/threonine-protein kinase RIO1; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its dynamic associa [...]	0.921
FAU	RPS15	ENSP00000431822	ENSP00000466010	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S15.	0.999
FAU	RPS18	ENSP00000431822	ENSP00000393241	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.	0.999
FAU	RPS2	ENSP00000431822	ENSP00000341885	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S2.	0.999
FAU	RPS21	ENSP00000431822	ENSP00000345957	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.	0.999
FAU	RPS23	ENSP00000431822	ENSP00000296674	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.999
FAU	RPS9	ENSP00000431822	ENSP00000375632	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S9.	0.999