DAPL1 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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Score

DAPL1

Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis. (107 aa)

Predicted Functional Partners:

PTN

0.979

FAU

0.886

RPL7A

0.853

RPL29

0.837

RPS23

0.837

RPL13

0.837

RPL5

0.837

RPL34

0.837

RPS29

0.837

RPS25

0.837

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAPL1	FAU	ENSP00000309538	ENSP00000431822	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	0.886
DAPL1	PTN	ENSP00000309538	ENSP00000341170	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	Pleiotrophin; Secreted growth factor that mediates its signal through cell- surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups. Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration in several tissues namely neuron and bone. Also plays a role in synaptic plasticity and learning-related behavior by inhibiting long-term synaptic potentiation (By similarity). Binds PTPRZ1, leading to neutralization of the negative charges of the CS ch [...]	0.979
DAPL1	RPL13	ENSP00000309538	ENSP00000307889	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	Ribosomal protein L13.	0.837
DAPL1	RPL29	ENSP00000309538	ENSP00000294189	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	60S ribosomal protein L29; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL29 family.	0.837
DAPL1	RPL34	ENSP00000309538	ENSP00000378163	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	60S ribosomal protein L34; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL34 family.	0.837
DAPL1	RPL5	ENSP00000309538	ENSP00000359345	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.837
DAPL1	RPL7A	ENSP00000309538	ENSP00000361076	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	Ribosomal protein L7a.	0.853
DAPL1	RPS23	ENSP00000309538	ENSP00000296674	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.837
DAPL1	RPS25	ENSP00000309538	ENSP00000435096	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	Ribosomal protein S25.	0.837
DAPL1	RPS29	ENSP00000309538	ENSP00000379339	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	Ribosomal protein S29.	0.837
FAU	DAPL1	ENSP00000431822	ENSP00000309538	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	0.886
FAU	RPL13	ENSP00000431822	ENSP00000307889	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein L13.	0.999
FAU	RPL29	ENSP00000431822	ENSP00000294189	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L29; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL29 family.	0.999
FAU	RPL34	ENSP00000431822	ENSP00000378163	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L34; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL34 family.	0.999
FAU	RPL5	ENSP00000431822	ENSP00000359345	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.999
FAU	RPL7A	ENSP00000431822	ENSP00000361076	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein L7a.	0.999
FAU	RPS23	ENSP00000431822	ENSP00000296674	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]	0.999
FAU	RPS25	ENSP00000431822	ENSP00000435096	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S25.	0.999
FAU	RPS29	ENSP00000431822	ENSP00000379339	Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion.	Ribosomal protein S29.	0.999
PTN	DAPL1	ENSP00000341170	ENSP00000309538	Pleiotrophin; Secreted growth factor that mediates its signal through cell- surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups. Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration in several tissues namely neuron and bone. Also plays a role in synaptic plasticity and learning-related behavior by inhibiting long-term synaptic potentiation (By similarity). Binds PTPRZ1, leading to neutralization of the negative charges of the CS ch [...]	Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.	0.979