node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMY2A | AMY2B | ENSP00000481450 | ENSP00000354610 | Pancreatic alpha-amylase; Amylase alpha 2A. | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | 0.960 |
AMY2A | PGA3 | ENSP00000481450 | ENSP00000322192 | Pancreatic alpha-amylase; Amylase alpha 2A. | Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.542 |
AMY2A | PGA4 | ENSP00000481450 | ENSP00000367391 | Pancreatic alpha-amylase; Amylase alpha 2A. | Pepsin A-4; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.555 |
AMY2A | PGA5 | ENSP00000481450 | ENSP00000309542 | Pancreatic alpha-amylase; Amylase alpha 2A. | Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.526 |
AMY2B | AMY2A | ENSP00000354610 | ENSP00000481450 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Pancreatic alpha-amylase; Amylase alpha 2A. | 0.960 |
AMY2B | PGA3 | ENSP00000354610 | ENSP00000322192 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.555 |
AMY2B | PGA4 | ENSP00000354610 | ENSP00000367391 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Pepsin A-4; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.558 |
AMY2B | PGA5 | ENSP00000354610 | ENSP00000309542 | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.520 |
CCHCR1 | PGA5 | ENSP00000379566 | ENSP00000309542 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation. | Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.629 |
CTSH | PGA3 | ENSP00000220166 | ENSP00000322192 | Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. | Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.530 |
CTSH | PGA4 | ENSP00000220166 | ENSP00000367391 | Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. | Pepsin A-4; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.531 |
CTSH | PGA5 | ENSP00000220166 | ENSP00000309542 | Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. | Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.529 |
F5 | PGA3 | ENSP00000356771 | ENSP00000322192 | Coagulation factor V heavy chain; Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. | Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.619 |
F5 | PGA4 | ENSP00000356771 | ENSP00000367391 | Coagulation factor V heavy chain; Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. | Pepsin A-4; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.623 |
F5 | PGA5 | ENSP00000356771 | ENSP00000309542 | Coagulation factor V heavy chain; Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. | Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.537 |
F5 | PROC | ENSP00000356771 | ENSP00000234071 | Coagulation factor V heavy chain; Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function ; Belongs to the peptidase S1 family. | 0.940 |
GLO1 | PGA5 | ENSP00000362463 | ENSP00000309542 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis. | Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.748 |
LGALS4 | PGA5 | ENSP00000302100 | ENSP00000309542 | Galectin-4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions. | Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | 0.649 |
PGA3 | AMY2A | ENSP00000322192 | ENSP00000481450 | Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | Pancreatic alpha-amylase; Amylase alpha 2A. | 0.542 |
PGA3 | AMY2B | ENSP00000322192 | ENSP00000354610 | Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. | Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family. | 0.555 |