Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C1orf100Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100. (147 aa)    
Predicted Functional Partners:
CFAP45
Cilia and flagella associated protein 45.
   
 
 0.881
C11orf1
UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.
    
   0.832
EFCAB6
EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.
    
   0.832
C7orf31
Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.
    
   0.832
ODF3B
Outer dense fiber of sperm tails 3B.
    
   0.832
hCG_1796489
HCG1796489.
    
   0.832
AK9
Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.
    
   0.788
TEPP
Testis, prostate and placenta expressed.
   
   0.706
C9orf135
Protein C9orf135; Chromosome 9 open reading frame 135.
   
   0.706
CCDC105
Coiled-coil domain containing 105.
   
   0.697
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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