STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR49WD repeat domain 49. (697 aa)    
Predicted Functional Partners:
SERPINI2
Serpin family I member 2.
 
 
  
 0.903
ZBBX
Zinc finger B-box domain containing.
 
 
  
 0.751
GOLGA8F
Golgin A8 family member F; Belongs to the GOLGA8 family.
   
  
 0.586
TMEM253
Transmembrane protein 253.
      
 0.583
PLEKHH3
Pleckstrin homology, MyTH4 and FERM domain containing H3.
      
 0.576
LRRC74A
Leucine-rich repeat-containing protein 74A; Leucine rich repeat containing 74A.
      
 0.573
GOLGA8G
Golgin A8 family member G.
   
  
 0.549
ARMCX2
Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells.
      
 0.529
FAM124A
Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family.
   
  
 0.513
CROCC2
Ciliary rootlet coiled-coil, rootletin family member 2; Belongs to the rootletin family.
      
 0.507
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.