WDR49 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB15	FRMD7	ENSP00000397655	ENSP00000298542	Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.	0.510
ASB15	GRIFIN	ENSP00000397655	ENSP00000481185	Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Grifin; Galectin-related inter-fiber protein.	0.464
ASB15	PLEKHH3	ENSP00000397655	ENSP00000468678	Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Pleckstrin homology, MyTH4 and FERM domain containing H3.	0.505
ASB15	WDR49	ENSP00000397655	ENSP00000311343	Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	WD repeat domain 49.	0.503
C20orf85	LRRC46	ENSP00000360210	ENSP00000269025	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46.	0.594
C20orf85	WDR49	ENSP00000360210	ENSP00000311343	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	WD repeat domain 49.	0.534
C20orf85	ZBBX	ENSP00000360210	ENSP00000390232	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	Zinc finger B-box domain containing.	0.418
FAM124A	SERPINI2	ENSP00000280057	ENSP00000481699	Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family.	Serpin family I member 2.	0.469
FAM124A	WDR49	ENSP00000280057	ENSP00000311343	Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family.	WD repeat domain 49.	0.510
FRMD7	ASB15	ENSP00000298542	ENSP00000397655	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.	Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.510
FRMD7	GRIFIN	ENSP00000298542	ENSP00000481185	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.	Grifin; Galectin-related inter-fiber protein.	0.453
FRMD7	PLEKHH3	ENSP00000298542	ENSP00000468678	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.	Pleckstrin homology, MyTH4 and FERM domain containing H3.	0.494
FRMD7	WDR49	ENSP00000298542	ENSP00000311343	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.	WD repeat domain 49.	0.509
GRIFIN	ASB15	ENSP00000481185	ENSP00000397655	Grifin; Galectin-related inter-fiber protein.	Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.464
GRIFIN	FRMD7	ENSP00000481185	ENSP00000298542	Grifin; Galectin-related inter-fiber protein.	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.	0.453
GRIFIN	PLEKHH3	ENSP00000481185	ENSP00000468678	Grifin; Galectin-related inter-fiber protein.	Pleckstrin homology, MyTH4 and FERM domain containing H3.	0.526
GRIFIN	WDR49	ENSP00000481185	ENSP00000311343	Grifin; Galectin-related inter-fiber protein.	WD repeat domain 49.	0.548
LRRC46	C20orf85	ENSP00000269025	ENSP00000360210	Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46.	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	0.594
LRRC46	WDR49	ENSP00000269025	ENSP00000311343	Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46.	WD repeat domain 49.	0.566
LRRC46	ZBBX	ENSP00000269025	ENSP00000390232	Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46.	Zinc finger B-box domain containing.	0.418