GPR162 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPR146	GPR148	ENSP00000380283	ENSP00000308908	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 148; Orphan receptor.	0.464
GPR146	GPR162	ENSP00000380283	ENSP00000311528	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 162; Orphan receptor.	0.518
GPR148	GPR146	ENSP00000308908	ENSP00000380283	Probable G-protein coupled receptor 148; Orphan receptor.	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.464
GPR148	GPR150	ENSP00000308908	ENSP00000369344	Probable G-protein coupled receptor 148; Orphan receptor.	Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.457
GPR148	GPR162	ENSP00000308908	ENSP00000311528	Probable G-protein coupled receptor 148; Orphan receptor.	Probable G-protein coupled receptor 162; Orphan receptor.	0.498
GPR150	GPR148	ENSP00000369344	ENSP00000308908	Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 148; Orphan receptor.	0.457
GPR150	GPR162	ENSP00000369344	ENSP00000311528	Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 162; Orphan receptor.	0.486
GPR150	GPR61	ENSP00000369344	ENSP00000432456	Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	G-protein coupled receptor 61; Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. May be involved in the regulation of food intake and body weight (By similarity).	0.447
GPR162	GPR146	ENSP00000311528	ENSP00000380283	Probable G-protein coupled receptor 162; Orphan receptor.	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.518
GPR162	GPR148	ENSP00000311528	ENSP00000308908	Probable G-protein coupled receptor 162; Orphan receptor.	Probable G-protein coupled receptor 148; Orphan receptor.	0.498
GPR162	GPR150	ENSP00000311528	ENSP00000369344	Probable G-protein coupled receptor 162; Orphan receptor.	Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.486
GPR162	GPR61	ENSP00000311528	ENSP00000432456	Probable G-protein coupled receptor 162; Orphan receptor.	G-protein coupled receptor 61; Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. May be involved in the regulation of food intake and body weight (By similarity).	0.495
GPR162	GPR62	ENSP00000311528	ENSP00000319250	Probable G-protein coupled receptor 162; Orphan receptor.	G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization.	0.563
GPR162	LRRC23	ENSP00000311528	ENSP00000390932	Probable G-protein coupled receptor 162; Orphan receptor.	Leucine-rich repeat-containing protein 23; Leucine rich repeat containing 23.	0.593
GPR162	MLF2	ENSP00000311528	ENSP00000203630	Probable G-protein coupled receptor 162; Orphan receptor.	Myeloid leukemia factor 2.	0.492
GPR162	PIANP	ENSP00000311528	ENSP00000442157	Probable G-protein coupled receptor 162; Orphan receptor.	PILR alpha-associated neural protein; Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation.	0.508
GPR162	TMEM167A	ENSP00000311528	ENSP00000424707	Probable G-protein coupled receptor 162; Orphan receptor.	Protein kish-A; Involved in the early part of the secretory pathway. Belongs to the KISH family.	0.484
GPR162	TMEM221	ENSP00000311528	ENSP00000342162	Probable G-protein coupled receptor 162; Orphan receptor.	Transmembrane protein 221.	0.570
GPR61	GPR150	ENSP00000432456	ENSP00000369344	G-protein coupled receptor 61; Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. May be involved in the regulation of food intake and body weight (By similarity).	Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.447
GPR61	GPR162	ENSP00000432456	ENSP00000311528	G-protein coupled receptor 61; Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. May be involved in the regulation of food intake and body weight (By similarity).	Probable G-protein coupled receptor 162; Orphan receptor.	0.495