node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNGA2 | RIC8B | ENSP00000328478 | ENSP00000376582 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily. | Synembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction; Belongs to the synembryn family. | 0.401 |
CNGA2 | RTP1 | ENSP00000328478 | ENSP00000311712 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily. | Receptor-transporting protein 1; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs; Belongs to the TMEM7 family. | 0.673 |
OR11H4 | OR2A7 | ENSP00000318997 | ENSP00000493320 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.514 |
OR11H4 | OR2B3 | ENSP00000318997 | ENSP00000366378 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Putative olfactory receptor 2B3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.499 |
OR11H4 | OR2L13 | ENSP00000318997 | ENSP00000493075 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 2L13; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.515 |
OR11H4 | OR2M7 | ENSP00000318997 | ENSP00000324557 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 2M7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.514 |
OR11H4 | OR5D18 | ENSP00000318997 | ENSP00000335025 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 5D18; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.542 |
OR11H4 | OR7D4 | ENSP00000318997 | ENSP00000493404 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 7D4; Odorant receptor. Selectively activated by androstenone and the related odorous steroid androstadienone. | 0.509 |
OR11H4 | REEP1 | ENSP00000318997 | ENSP00000392197 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Receptor expression-enhancing protein 1; Required for endoplasmic reticulum (ER) network formation, shaping and remodeling; it links ER tubules to the cytoskeleton. May also enhance the cell surface expression of odorant receptors. May play a role in long-term axonal maintenance. | 0.444 |
OR11H4 | RTP1 | ENSP00000318997 | ENSP00000311712 | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Receptor-transporting protein 1; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs; Belongs to the TMEM7 family. | 0.612 |
OR2A7 | OR11H4 | ENSP00000493320 | ENSP00000318997 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.514 |
OR2A7 | OR2B3 | ENSP00000493320 | ENSP00000366378 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Putative olfactory receptor 2B3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.512 |
OR2A7 | OR2L13 | ENSP00000493320 | ENSP00000493075 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 2L13; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.548 |
OR2A7 | OR2M7 | ENSP00000493320 | ENSP00000324557 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 2M7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.515 |
OR2A7 | OR5D18 | ENSP00000493320 | ENSP00000335025 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 5D18; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.531 |
OR2A7 | OR7D4 | ENSP00000493320 | ENSP00000493404 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 7D4; Odorant receptor. Selectively activated by androstenone and the related odorous steroid androstadienone. | 0.517 |
OR2A7 | REEP1 | ENSP00000493320 | ENSP00000392197 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Receptor expression-enhancing protein 1; Required for endoplasmic reticulum (ER) network formation, shaping and remodeling; it links ER tubules to the cytoskeleton. May also enhance the cell surface expression of odorant receptors. May play a role in long-term axonal maintenance. | 0.509 |
OR2A7 | RTP1 | ENSP00000493320 | ENSP00000311712 | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Receptor-transporting protein 1; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs; Belongs to the TMEM7 family. | 0.614 |
OR2B3 | OR11H4 | ENSP00000366378 | ENSP00000318997 | Putative olfactory receptor 2B3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 11H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.499 |
OR2B3 | OR2A7 | ENSP00000366378 | ENSP00000493320 | Putative olfactory receptor 2B3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 2A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.512 |